The results confirmed that the alcohol (ethanol) was being converted to acetaldehyde, causing DNA damage and switching on the cell's DNA repair genes.
结果表明,酒精(乙醇)转换成乙醛后破坏dna,激活细胞内dna的修复基因。
Objective To investigate the association of polymorphisms of metabolic and DNA repair enzyme genes and DNA damage in peripheral blood lymphocytes in coke-oven workers.
目的研究外源性化学物代谢酶和DNA损伤修复酶基因多态性与焦炉作业工人外周血淋巴细胞DNA损伤易感性的关系。
Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.
结论苯中毒患者外周血白细胞的DNA复制及损伤修复基因与正常人相比存在差异性表达,为进一步筛选苯中毒生物标志物提供了依据。
Objective To screen DNA replication, and damage repair genes associated with benzene poisoning by using gene expression profile analysis.
目的筛选与苯中毒有关的DNA复制及损伤修复基因。
Looking at cells in a dish, the team found that mistakes in these genes prevented the cells from being able to repair damage to their DNA.
研究团队调查研究一个盘子里的细胞,发现这些基因的缺陷能够阻止细胞修复对它们DNA的损害。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
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