For fluoxetine and paroxetine, dosage cutting is needed in case of coadministration with CYP2D6 substrates.
与治疗窗较窄的CYP2D 6底物合用时，应注意帕罗西汀和氟西汀的剂量调整。
Coadministration of hypothalamic PKC - inhibitor rottlerin with OAG prevented the ability of OAG to activate PKC - and lower glucose production.
下丘脑蛋白激酶C抑制剂卡马拉素和OAG同时给药会抑制OAG活化蛋白激酶c的能力并降低葡萄糖的生成。
Meanwhile, many drugs can influence the activity of CYP2D6 by competitive inhibition or induction, which is easy to cause interaction in coadministration.
而且CYP2D6能被多种药物竞争性抑制和诱导，药物联用时易产生相互作用。
However, monitoring may be more important during coadministration of aminoglycosides or other ototoxic agents level of evidence, 3; grade of recommendation,.
不过，监测可能更氨基糖苷类期间或其他耳毒性药物合用重要一级证据，3，等级的建议，。
Coadministration of other known cytochrome P 450 isoenzyme 3A4 inducers (eg, phenytoin and phenobarbital) may lead to similar decreases in risperidone levels and loss of therapeutic effect.
共同服用其他已知的细胞色素P450同工酶3A4（苯妥英和镇静安眠剂）可能导致相似的利培酮水平的降低并失去治疗效果。
Coadministration of other known cytochrome P 450 isoenzyme 3A4 inducers (eg, phenytoin and phenobarbital) may lead to similar decreases in risperidone levels and loss of therapeutic effect.
共同服用其他已知的细胞色素P450同工酶3A4（苯妥英和镇静安眠剂）可能导致相似的利培酮水平的降低并失去治疗效果。
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