Also disclosed are pharmaceutical compositions comprising such anti-RAGE antibodies and RAGE-binding antibody fragments thereof, and their use for treatment of RAGE related diseases.
本发明也揭示包含所述抗rage抗体及其RAGE结合抗体片段的医药组合物及其用于治疗RAGE相关疾病的用途。
If there is a virus antigen of antigen antibody binding, is.
如病损中有病毒抗原,则抗原抗体结合。
After incubation of virus with its antiserum, the antiserum that can inhibit virus binding ability to the cells should contain neutralizing antibody.
当病毒与抗血清保温后,抑制病毒与细胞的吸附能力的抗血清中应含有中和抗体。
Methods:Applying the principle of specific binding of antibody and antigen, make detection on accurate localization and qualitaliveness in tissues and cells.
方法利用抗原、抗体特异性结合原理,在组织和细胞中进行抗原、抗体准确定性、定位的检测。
The membrane provides a uniform pore and, thus, a liquid–solid interface for reproducible antigen–antibody binding.
膜拥有统一的孔径,从而也就有了能用于可重复的进行抗原抗体结合的液固界面。
The reliability of the method was confirmed by site-directed mutagenesis, selective chemical modification, site-specific antipeptide antibody binding experiments, and so on.
大量定点突变实验、选择性化学修饰实验、抗多肽抗体结合实验等能很好地确证该联配结果的正确性。
Antibodies against SARS virus were screened by biopanning with immobilized virus antigen. The binding specificity of phage antibody to SARS virus was detected by ELISA.
以固相化的SARS抗原淘筛抗体库,并用ELISA检测噬菌体抗体结合SARS病毒的特异性。
Monoclonal antibody is produced by immunizing animals with phospho-(Ser) 14-3-3 binding motif peptides .
该单克隆抗体用磷酸化丝氨酸14-3-3结合基序多肽免疫动物制备。
The binding process of antigen and antibody completed in the solution, which doesn't have the shortage of conformational changes encountered in the immobilized screening.
整个筛选过程中抗原与抗体的结合在液相中完成,不仅消除了固相介质对抗原表位的影响,也更有利于噬菌体抗体与抗原的充分作用。
It may be that the antigen structure was effected by the different ELISA methods, so that the capability of the binding of antigen to antibody was changed.
这可能由于ELISA方法对抗原结构的影响而导致抗原抗体结合的不同。
Antibody can be linked to liposome particles by covalent binding.
抗体能通过共价键结合在脂质体颗粒上。
Put radioactive material with a special antibody binding, radiation will be aimed at the expression of the corresponding antigen cells, which would reduce the harm to other organizations.
把放射性物质与特殊抗体结合,放射就会针对表达相应抗原的细胞,这样就会减少对其他组织的伤害。
A test on the antigen-antibody binding reaction has been done by the SPR sensor which we designed - to study the appropriate proportion between the antigen and the antibody.
利用自行初步设计的SPR传感仪,对抗原抗体结合反应进行测试,分析研究结合反应中两者的适宜比例。
Specific antibody was screened by 3 rounds of panning of phage antibody library with the fusion protein. The antigen binding activity and DNA sequences of positive clones were determined and analyzed.
以该融合蛋白为固相抗原,对噬菌体抗体库进行3轮淘筛,并对所获阳性克隆进行抗原结合活性测定和DNA序列测定。
Because the analyte molecules are recognized by forming the binding complex with antibody, a decrease in the detection limit is achieved only by an increase in the reaction yield.
因为分析物分子能通过与抗体形成结合物而被发现,所以降低检测极限只能通过增加反应产率来达到。
This results from the competition between the fixed and free antigen for binding to the labeled antibody.
这是由固定和自由的抗原对标记抗体的竞争结合导致的。
Using such gels prevents the nonspecific adsorption of antibody-binding molecules.
使用这样的凝胶防止了抗体结合分子的非特异性吸附。
Binding of the tetramers occurred by the surface immunoglobulin antigen receptor with little or no binding to antibody captured in the Fc receptor.
四聚物的结合是通过表面免疫球蛋白抗原受体,通过Fc受体结合抗体的很少量甚至没有。
The binding ability of these deletant proteins to AD5-10, a mouse anti-human DR5 monoclonal antibody, was evaluated by immunoblotting and ELISA.
利用蛋白免疫印迹及ELISA技术研究重组蛋白与小鼠抗人DR5单克隆抗体AD5-10的结合情况。
The theory is to utilize the specific binding reaction and immunochromatography technique of antigen antibody, with specific chromogenic results on test paper.
其原理是利用抗原抗体的特异结合反应和免疫层析技术,在试纸上出现特定的显色结果。
Analysis on the structure and function of antibody for providing theoretical basis to study antigen-antibody binding reaction.
对抗体的结构功能进行分析,为研究抗原抗体结合反应提供理论基础。
Objective to observe specific binding ability of anti-PNAS-2 single chain antibody with PNAS-2 antigen and its effects on apoptosis of human leukemic U937 cells.
目的观察抗PNAS - 2单链抗体与PNAS - 2抗原特异性结合的能力,并在此基础上探究其对急性单核细胞白血病u 937细胞凋亡的影响。
This permits the formation of binding complex between the labeled antibody and analyte in the void space of glass fibers.
这就使得标记抗体和分析物间结合物的形成在玻璃纤维的空的空间里进行的。
This suggested that the antibody components indeed have binding activity in the midgut.
结论:蚊幼虫肠细胞膜泡抗体组分与肠壁具有结合作用。
Analysis on the structure and function of antibody provides theoretical basis to study the properties of antibody and antigen-antibody binding reaction.
对抗体蛋白进行的结构功能分析为研究抗体性质及与抗原反应机理提供理论基础。
The antibody then participates in the binding reaction to form a complex with the analyte in the liquid phase.
然后抗体参与结合反应,在水溶液中形成了带有分析物的复合物。
In particular, the cell binding agent is a monoclonal antibody, and epitope-binding fragments thereof, that recognizes and binds the CD38 protein.
特别的,细胞结合剂是识别并结合CD38蛋白的单 克隆抗体、其表位结合片段。
Preferred antibodies of the invention specifically bind a conformational epitope predominant to native human TF, which epitope provides an unexpectedly strong antibody binding site.
优选本发明抗体可特异性结合天然人类TF的主要构象抗原决定部位,该抗原决定部位提供意想不到的强力抗原决定簇。
Preferred antibodies of the invention specifically bind a conformational epitope predominant to native human TF, which epitope provides an unexpectedly strong antibody binding site.
优选本发明抗体可特异性结合天然人类TF的主要构象抗原决定部位,该抗原决定部位提供意想不到的强力抗原决定簇。
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