Objective To investigate the effects of BCNU on the proliferation and cell cycle of stem cells from human brain tumor.
目的：探讨卡莫司汀对人脑肿瘤干细胞在细胞增殖及细胞周期方面的影响。
Conclusion BCNU loaded PLGA wafer can inhibit the proliferation of C6 glioma cell and demonstrate gradually increased tendency with prolonged release time.
结论BCNU PLGA缓释微球可以抑制C6胶质瘤细胞的增殖，随释放时间延长细胞生长抑制率逐渐上升。
Results: The focal cerebral necrosis resulted from the BCNU toxicity of the blood vessels and cerebral nerves, and it is related to the way of infusion and drug quantities.
结果：局限性脑组织坏死为BCNU的血管毒性和神经毒性造成，与给药途径有关。
Conclusion This high performance liquid chromatography method is simple, sensitive and accurate. It is suitable for released kinetics study of controlled-release microspheres of BCNU loading in vitro.
结论本法准确可靠，操作简便，适用于缓释bcnu微球的体外药物释放动力学研究。
Conclusion This high performance liquid chromatography method is simple, sensitive and accurate. It is suitable for released kinetics study of controlled-release microspheres of BCNU loading in vitro.
结论本法准确可靠，操作简便，适用于缓释bcnu微球的体外药物释放动力学研究。
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