Objective To investigate the effect of 5-azacytidine on cardiomyogenic differentiation of bone marrow mesenchymal stem cells (BMSCs).
目的研究在体外5-氮胞苷诱导骨髓间质干细胞定向心肌向分化的条件。
Bone marrow stem cells of young rats can form immature myocardial-like cells after in vitro culture labeling of 5-bromodeoxyuridine and induction of 5-azacytidine.
幼鼠骨髓干细胞经体外培养、5 -溴脱氧尿核苷标记和5 -氮杂胞嘧啶核苷诱导能形成幼稚的心肌样细胞。
AIM: To study morphological and molecular biological feature of differentiation of umbilical cord blood stem cells in vitro after induced by 5-azacytidine into cardiomyocytes.
目的:观察脐血间充质干细胞经5-氮杂胞苷诱导在体外定向分化为心肌样细胞的形态学及分子生物学特征。
Results Mesenchymal stem cells were spindle-shaped and active proliferation capacity in vitro, they can be differentiation into cardiac-like muscle cells after adding 5-azacytidine.
结果大鼠骨髓基质细胞贴壁呈集落生长,5 -氮胞苷诱导骨髓基质细胞转化为心肌样细胞。
Objective To investigate the effects of electrical stimulation on the differentiation of rat bone marrow mesenchymal stem cells (MSCs) to cardiomyocyte induced by 5-azacytidine in vitro.
目的探讨脉冲微交流电刺激对体外诱导大鼠骨髓间充质干细胞向心肌样细胞分化的作用。
Objective To investigate the effects of electrical stimulation on the differentiation of rat bone marrow mesenchymal stem cells (MSCs) to cardiomyocyte induced by 5-azacytidine in vitro.
目的探讨脉冲微交流电刺激对体外诱导大鼠骨髓间充质干细胞向心肌样细胞分化的作用。
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