Strong evidence has showed the role of apoptosis in ARF. Caspases serve as one of the mediators in apoptosis pathway.
大量证据证明了凋亡在急性肾功能不全中的作用。
Apoptosis-associated proteins regulate apoptosis through taking part in the apoptosis pathway and the signal transduction in apoptosis.
颗粒细胞凋亡相关蛋白通过参与凋亡通路及凋亡信号转导调节凋亡。
Objective to research the dynamic changes of cardiomyocyte apoptosis and the mechanism of mitochondria apoptosis pathway in rats after coronary microembolization.
目的探讨大鼠冠状动脉微栓塞后心肌细胞凋亡及其线粒体途径激活的动态变化规律。
Conclusion: PC has a protective effect on cerebral IR injury, which may related to increased GRP78 and decreased CHOP expression, and to inhibition of the ERS-induced apoptosis pathway.
结论：PC对脑缺血再灌注损伤大鼠具有保护作用，其机制可能与其增加GRP78表达、拮抗chop表达、阻断内质网应激(ERS)启动的凋亡通路有关。
In this review, the common pathway of apoptosis and the regulation in the placenta are described.
本文主要评述细胞凋亡的一般通路以及胎盘发生过程中细胞凋亡的调控。
Further elucidation of the signal pathway leading to cardiomyocyte apoptosis may open new routes to prevention and treatment of CHF.
进一步阐明心肌细胞凋亡的信号通路，将为CHF的预防和治疗提供新的途径。
Conclusion EGCG induces apoptosis of BGC823 cells via activating mitochondrial signal transduction pathway.
结论EGCG通过活化线粒体信号传导途径诱导BGC823细胞凋亡。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂，能阻断酪氨酸蛋白激酶信号传导通路，从而促进肿瘤细胞凋亡。
MAPK signaling transduction is a key pathway of cellular proliferation and apoptosis regulation.
MAPK信号转导通路是一条关键的调节细胞增生和凋亡的通路。
Objective To explore the relationship between immune dysfunction and disturbance of lymphocytic apoptosis signal transduction pathway in patients with systemic lupus erythematosus (SLE).
目的探讨SLE患者免疫功能紊乱与淋巴细胞凋亡信号传导途径异常之间的关系。
Objective: to investigate the pathway of C. albicans-induced murine thymocyte apoptosis.
目的：探讨白色念珠菌诱导小鼠胸腺细胞凋亡的通路。
Objective to elucidate the mechanism of apoptosis induced by epigallocatechin-3-gallate (EGCG) on human gastric cancer BGC823 cells via mitochondrial pathway.
目的探讨表没食子儿茶素没食子酸酯(EGCG)通过活化线粒体途径诱导人胃癌BGC823细胞凋亡的作用机制。
Objective To investigate the molecular pathway of apoptosis of U937 cells in myelocytic leukemia cell lines induced by trichostatin A(TSA).
目的研究曲古菌素A（TSA）诱导髓系白血病细胞株U937细胞凋亡的分子途径。
Conclusion: Matrine can induce C6 glioma cell apoptosis and the mechanism might be related to a number of genes involved in death receptor pathway and mitochondrial pathway.
结论：苦参碱能诱导C6胶质瘤细胞的凋亡，其机制与死亡受体途径和线粒体途径的众多基因有关。
Aim to evaluate the effect of 5 LOX pathway in gastric cancer and the potential role pharmacological inhibition of 5 LOX on induction of apoptosis in gastric cancer cells.
目的评价5脂质加氧酶(5LOX)代谢途径在胃癌中的作用及5 LOX抑制剂对胃癌细胞凋亡的影响。
One additional pathway is accelerating the potential role of apoptosis or death of activated stellate cells without harming the surrounding cells.
另外一个途径是加速活化星状细胞凋亡或死亡而不损伤周围细胞的潜在作用。
CONCLUSION Cd-induced apoptosis involves mitochondrial pathway in HEK293 cells.
结论镉诱导HEK293细胞的凋亡可能通过线粒体途径。
Conclusions Curcumin induced apoptosis of NCE cells both through mitochondria-dependent pathway and death receptor pathway.
结论姜黄素可能通过线粒体途径与死亡受体途径诱导鼻咽癌nce细胞凋亡。
Our results further showed that the PD-1/PD-L1 pathway which could reduce the rate of T lymphocyte apoptosis via the death receptor pathway of endogenous and exogenous death receptor pathway.
我们的结果还进一步表明PD-1／PD-L1途径对T淋巴细胞凋亡的影响是同时通过内源性死亡受体途径和外源性死亡受体途径产生的。
Conclusion: NTD embryos were induced by PMX, the mechanism of which might be PMX inhibited folate metabolism pathway and led to decreased cellular proliferation and excessive cellular apoptosis.
结论：PM X能诱导NTD的发生，其机制可能是因为PMX阻断了叶酸代谢通路并导致神经上皮细胞的增殖抑制和过度凋亡。
CONCLUSION: Acetaldehyde causes oxidative damage in cardiomyocytes through enhancing cellular ROS level, and induces cardiocytes apoptosis by activating ROS mediated JNK pathway.
结论：乙醛通过增高胞内ros水平损伤心肌细胞，激活ros介导JNK途径诱导细胞凋亡。
Conclusion the apoptosis of PC-3 cells induced by oridonin might be associated with the mitochondrial pathway.
结论：冬凌草甲素可能通过线粒体途径诱导PC - 3细胞凋亡。
Objective to investigate the role of ubiquitin-proteasome pathway (UPP) in the regulation of retinal cell apoptosis after experimental retinal detachment (RD).
目的探讨泛素-蛋白酶体通路(UPP)在实验性视网膜脱离(RD)中对视网膜细胞凋亡的调控作用。
JNK signaling transduction pathway plays a vivtal role in the neuronal apoptosis.
JNK信号转导途径参与神经元凋亡。
In recent years, the study found that the apoptosis mechanism of endoplasmic reticulum stress-mediated apoptosis is a new signaling pathway of apoptosis.
近年来在凋亡机制的研究中发现内质网应激反应介导的细胞凋亡是一条新的细胞凋亡信号传导通路。
Mitogen-activated protein kinase pathway may closely associated with cell growth, differentiation and apoptosis, it may play an important role in cell death.
促有丝分裂原活化蛋白激酶（MAPK）信号传导途径与细胞生长、分化、凋亡等密切相关，在介导细胞凋亡过程中起着重要作用。
Objective To investigate the possible pathway of the effect of all-trans retinoic acid(ATRA) on the apoptosis of human breast cancer cell line(MCF-7).
目的：探讨全反式维甲酸（ATRA）对人乳腺癌MCF-7细胞凋亡的影响及作用途径。
This suggests the diminished expression of NGF and impairment of neuron survival signal transduction pathway may be one of the reason of apoptosis in AD brains.
AD患者颚叶神经营养因子及其受体表达减少。神经营养因子表达的减少以及存活信号转导通路的损害可能是导致ad脑神经元凋亡的原因之一。
This suggests the diminished expression of NGF and impairment of neuron survival signal transduction pathway may be one of the reason of apoptosis in AD brains.
AD患者颚叶神经营养因子及其受体表达减少。神经营养因子表达的减少以及存活信号转导通路的损害可能是导致ad脑神经元凋亡的原因之一。
应用推荐