Before androgen ablation treatment, the androgen independent cancer cells are already existed.
在进行抗雄激素治疗之前，雄激素非依赖型“癌”细胞已经存在。
However, over time cancer cells can become "androgen independent," and grow even in the presence of these medications.
但是，经过一段时间癌细胞可以变为雄激素非依赖性，即使在维持这种治疗情况下肿瘤仍然继续生长。
Objective To study the inhibition of vibramycin on the expression of matrix metalloproteinase 2 (MMP 2) and the invasiveness of androgen independent prostatic carcinoma cell line PC 3 in vitro.
目的探讨强力霉素对雄激素非依赖型前列腺癌PC3细胞基质金属蛋白酶2 (MMP 2)表达的抑制及与体外侵袭能力的关系。
It recognized even androgen-independent cancer cells, present when prostate cancer is incurable, the study by researchers at the University of Pennsylvania showed.
宾夕凡尼亚州大学的研究者说，即便是在目前来说不可治愈的非雄激素依赖性前列腺癌中也是有效的。
AIM: To study the role of androgen receptor (AR) in hormone-dependent and hormone-independent prostate cancer cell proliferation by knocking down AR expression with adenovirus-delivered siRNA.
目的：利用RNA干涉技术抑制雄激素受体（AR）的表达，研究AR在激素依赖性和激素非依赖性前列腺癌细胞增殖中的作用。
The mutation of androgen receptor gene, abnormal phosphorylation and abnormal regulation of co-activators contribute to the formation of androgen-independent prostate cancer.
雄激素受体基因突变、多种途径引起的异常磷酸化激活和共激活物的调节失控等是激素非依赖性前列腺癌形成的主要促成因素。
CONCLUSION: Multiple factors, including the different expression of ar isoforms, contribute to the development of androgen-independent growth of prostatic carcinoma cells.
结论：前列腺癌进展是多因素作用的结果，其中包括AR亚型的差异性表达。
CONCLUSION: Multiple factors, including the different expression of ar isoforms, contribute to the development of androgen-independent growth of prostatic carcinoma cells.
结论：前列腺癌进展是多因素作用的结果，其中包括AR亚型的差异性表达。
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