• On transcriptional level, no foregone alternative splicing event was found.

    转录水平,发现了新的异常剪接基因。

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  • We demonstrated a direct role for histone modifications in alternative splicing.

    我们证明了组蛋白修饰选择性剪接中一个直接作用

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  • CD72 is a B cell specific receptor that exists in multiple alternative splicing forms.

    CD 72一个重要的B细胞特异性受体,它多种选择性剪切形式存在

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  • Moreover, the rate of transcription elongation has been linked to alternative splicing.

    此外转录延伸速率可变剪接相关

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  • This shift in alternative splicing may reflect an attempt of tissue repair and remodeling.

    这种选择性连接的转变可能反映了组织修复重建某种尝试

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  • Alternative splicing plays an important role in processes such as development, differentiation and cancer.

    可变剪接在发育分化和癌症过程发挥非常重要作用

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  • Studying alternative splicing mechanism is of great significance to understanding eukaryote gene regulation.

    研究基因可变剪接理解真核生物基因调控具有十分重要的意义。

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  • Problems about mechanisms control alternative splicing is a leading research endeavors in functional genome era.

    有关选择性剪接调控机制功能基因组时代重要前沿问题之一。

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  • The unique alternative splicing makes ZNF191, ZNF396 and ZNF397 genes encode two distinct proteins respectively.

    这种独特的变异剪接形式使ZNF191、ZNF396ZNF397基因分别产生两种不同蛋白质

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  • Spliced alignment is a sequence alignment method which considers the different alternative splicing forms during alignment.

    剪接比对指的比对过程中考虑不同选择性剪接方式序列比对方法

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  • Alternative splicing is often regulated in tissue-and developmental stage-specific manner, or in response to extracellular stimuli.

    可变剪接具有高度的组织发育阶段特异性,并受到外界信号的控制。

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  • A heuristic algorithm for multiple alignment was developed to more effectively study alternative splicing patterns of eukaryotic genes.

    为对真核基因选择性剪接形式进行准确、快速、有效研究,提出了一种启发式序列比对算法

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  • Spliceosome assembly occurs co-transcriptionally, raising the possibility that DNA structure may directly influence alternative splicing.

    剪接组装与转录同步进行,提示DNA结构可能直接影响可变剪接。

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  • Alternative splicing didn't help either: it could be argued that it represents a case of RNA making itself, then making a bunch of different proteins.

    选择性拼接不肯帮忙可以看作另外一种例外——RNA还能自我复制,然后制造一揽子形形色色蛋白质

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  • Alternative splicing is generally believed to occur more than 50% of actively transcribed human genes and thus is highly relevant to disease and therapy.

    人类基因中超过50%转录产物进行选择性剪接,而这机制疾病发生、治疗方法高度相关性

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  • This work demonstrate a molecular mechanism for the creation of novel proteins through alternative splicing in the central nervous system during human evolution.

    本项研究表明人类起源,基因剪切的变化可能是导致人脑产生新的蛋白质进而出现新功能重要机制之一。

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  • In recent years, more and more researches showed that alternative splicing was highly relevant to cancer, and many cancer genes were regulated by alternative splicing.

    近年来,越来越多的研究表明可变剪接癌症有着密切的关系,许多癌症相关基因可变剪接调控。

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  • The researchers discovered this transition in cancer cells when they observed an error in "alternative splicing, " a key element of the genetic copying program inside cells.

    科学家们通过观察选择剪切发现一个错误,在癌细胞中发现了这种转变

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  • Until 20 years ago, scientists believed that a single gene made a single protein. With the discovery of alternative splicing, it became clear that one gene can produce multiple proteins.

    20年前科学家们认为基因对应一个蛋白发现选择性剪切知道个基因可以生成多种不同蛋白

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  • Until 20 years ago, scientists believed that a single gene made a single protein. With the discovery of alternative splicing, it became clear that one gene can produce multiple proteins.

    20年前科学家们认为基因对应一个蛋白发现选择性剪切知道个基因可以生成多种不同蛋白

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