实验结果表明，荧光恢复程度与靶蛋白的浓度正相关。
The results show that the fluorescence resuming ratio is proportional to the concentration of target protein.
其它微点阵的用途包括从大量分子中筛选出能结合特定靶蛋白的分子。
Other uses of microarrays include the screening of large numbers of molecules for their capacity to bind a particular target protein.
为了研究特异靶蛋白，必须防止蛋白酶介导的蛋白发生降解。
In order to study specific target proteins of interest protease-mediated degradation during the generation of protein lysates is to be avoided.
为了研究特异靶蛋白的磷酸化状态，磷酸化的残基必须保持完整。
In order to study the phosphorylation status of specific target proteins the phosphorylated residue of interest must remain intact.
组合化学与大规模筛选相结合用于识别与治疗用靶蛋白结合的化合物即潜在新药。
Combinatorial chemistry is used in tandem with high-throughput screening to identify compounds that bind to a therapeutic target protein and are thus potential new drugs.
向细胞裂解液中加入蛋白酶抑制剂后可以保护细胞提取物中的靶蛋白。
The addition of protease inhibitors to the cell lysis buffer AIDS in the preservation of target proteins in the cell extract.
用小型的、自动机技术针对靶蛋白、细胞或组织筛选大量化合物文库以识别潜在新药。
The use of miniaturized, robotics-based technology to screen large compound libraries against an isolated target protein, cell or tissue in order to identify binders that may be potential new drugs.
目前研究表明往往需多种方法联合使用才能阐明特定药物与其靶蛋白的相互作用。
It has been showed that combined usages of several technologies are always needed to elucidate an interaction between drug and protein.
我们着重研究以下几个问题：1确定上述几种调节衰老的途径是否共用一组靶蛋白。
We are particularly interested in the following questions. 1 do these mechanisms act on a common set of downstream targets to control lifespan?
斯特朗及其同事最近发现，更多的人清楚认为雷帕霉素靶蛋白通道在各个物种间间重要性。
But the new finding by Strong and his colleagues "more clearly identifies the [target of rapamycin] pathway as important across species."
CDK引起的细胞周期依赖性磷酸化会抑制Rb与靶蛋白结合从而促进细胞周期的进行(5)。
Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression (5).
包括铜离子的摄取、细胞内转运、将配至靶蛋白、以至最终排出细胞的各个过程都相互衔接，受到这个调控体系的精密调节。
Such procedures as copper uptake, transportation, assembly and excretion are adjoined to one another and manipulated exquisitely by this regulation system.
孙俊锋，棘怀庆，雄英，李宗吉，王娅娜，赵巍【摘要】目的用生物信息学方法从世界权威数据库检索筛选能用于诊断或治疗的细粒棘球蚴靶蛋白。
Objective To screen specific target proteins for early diagnosis or therapy of echinococcosis by screening the authoritative databases from all over the word with bioinformatics method.
此复合体中P23作为HSP90的伴侣分子，能够和HSP90特异性结合，调节HSP90与ATP或ADP结合的形式而达到结合或释放靶蛋白的功能。
P23, as one co-chaperone of HSP90, could bind to HSP90 specially, let HSP90 bind or release the target protein by regulating the form of the HSP90 binding with ATP or ADP.
好的蛋白结构分辨率对于对于很多应用都是非常重要的，包括但不限于虚拟筛选药物靶点与对接程序和蛋白质设计。
Better resolution is important for a number of applications, including but not limited to virtual screening of drug targets with docking procedures and protein design.
而弄清楚这些分子的结构有助于科学家们去研究那些由畸形蛋白质引起的疾病，并找出更好的药物靶点。
Figuring out such structures could help scientists learn more about diseases caused by malformed proteins and identify better drug targets.
首先，要有一个大的载体蛋白来构成给靶物质的平台。
First, there is a large carrier protein that forms a platform for the target.
专家们在文中写道：这项研究揭示了一种新型蛋白转运装置的属性，因此为抗疟药物研发者提供了一个新的靶点。
"This study reveals the identity of a novel protein trafficking apparatus... and hence, provides an 'Achilles heel' for anti-malaria drug developers," they wrote.
这是非常重要的，因为如果这未发生，蛋白质从细胞中出来进到其靶位置，严重疾病将会因而产生并杀伤有机体。
This is very important because if it doesn't happen, the proteins get out of the cell to their targets and severe disease will ensue and kill the organism.
我们把该列表交给了大学，制药厂，生物科技公司，开始开发新的药物，因为这些突变基因及其蛋白质是新的治疗靶点。
We hand that list over to the universities, the pharmaceuticals, the biotech companies to start developing new drugs because those mutated genes and their proteins are targets for new therapeutics.
这项研究的重要性在于可以准确了解病毒蛋白的结构，将其薄弱处作为治疗靶点，进而开发出更好的治疗方法。
It is important to know exactly how viral proteins are structured so that drug developers can target weaknesses within it, and therefore devise better treatments for people.
此外，组蛋白乙酰转移酶的活性对HIV的增殖是必要的，至少一个科学小组建议组蛋白乙酰转移酶或相似的酶做为靶点也许是抑制病毒一个新方式。
In addition, hat activity is necessary for the multiplication of HIV, leading at least one scientific group to suggest that targeting HATs or similar enzymes might be an new way to thwart the virus.
蛋白偶联受体具有重要的生理功能和病理意义，已成为一类重要的药物靶点。
Protein-coupled receptors are a group of drug targets with important physiological functions and of pathological significance.
为了了解LXR如何调节低密度脂蛋白受体，作者研究了LXR靶基因的转录，并确定了一个能编码肌球蛋白互动蛋白的基因，IDOL。
To understand how LXR regulates LDLR, the authors examined transcriptional target genes of LXR and identified a gene that encodes a myosin interacting protein, IDOL.
在染色体中，SATB1还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。
SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci.
基质金属蛋白酶(MMP)因其在肿瘤的生长、转移和血管生成等多个环节中发挥着重要作用而成为肿瘤治疗研究中引人注目的靶点。
Matrix metalloproteinases (MMPs) has been viewed as a promising target in tumor therapy due to their key role in tumor growth, angiogenesis, invasion and metastasis.
近几年来，基质金属蛋白酶因在肿瘤的生长、转移和血管生成等多个环节中发挥着重要作用而成为肿瘤治疗研究中引人注目的新靶点。
Matrix metalloproteinases (MMPs) has been viewed as a promising target in tumor therapy in recent years due to their key role in tumor growth, angiogenesis, invasion and metastasis.
近几年来，基质金属蛋白酶因在肿瘤的生长、转移和血管生成等多个环节中发挥着重要作用而成为肿瘤治疗研究中引人注目的新靶点。
Matrix metalloproteinases (MMPs) has been viewed as a promising target in tumor therapy in recent years due to their key role in tumor growth, angiogenesis, invasion and metastasis.
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