本发明涉及一类肿瘤靶向性大分子控制释放抗癌药物及制备方法和用途。
The invention relates to a tumor targeting macromolecule controlled release anticancer drug and a preparation method and USES thereof.
背景与目的：口服结肠靶向给药系统(OCDDS)是一种将药物定位释放于结肠的靶向制剂。
Background and Objective: OCDDS (Oral Colon-specific drug delivery system) is a kind of drug target delivery systems, which can deliver drug at colon.
理想的纳米粒载体应有特异靶向性、药物释放可控性，无毒性以及可生物降解等。
The perfect nanoparticle vectors should be specific-targeting, controlled release, nontoxicity? biodegradation, and so on.
生物可降解型高分子载体控制释放药物和生物可降解型高分子载体靶向药物是近年来高分子药物研究的重点。
Biodegradable macromolecule carried controlled drug releasing and biodegradable macromolecule carried targeted drug delivery are the focus of recent investigation in macromolecular medicine.
本论文针对普通药物剂型和给药方式的不足，开展靶向性药物控制释放新制剂的研究。
In this thesis, a significant research on targeted drug-loaded magnetic polymer microspheres has been carried out as to the deficiency of normal drug administration.
构建一种药物载体使其能顺利穿透细胞膜并在靶向部位释放，已成为药物设计中亟需解决的问题之一。
To design a new drug vector for promoting the agents across cellular membrane and releasing at the target issues is a persistent challenge.
构建一种药物载体使其能顺利穿透细胞膜并在靶向部位释放，已成为药物设计中亟需解决的问题之一。
To design a new drug vector for promoting the agents across cellular membrane and releasing at the target issues is a persistent challenge.
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