结直肠癌的肿瘤微环境是个复杂的群落,有基因突变的癌细胞、非肿瘤细胞和多种多样的微生物群。
The tumor microenvironment of colorectal carcinoma is a complex community of genomically altered cancer cells, nonneoplastic cells, and a diverse collection of microorganisms.
目的在非免疫非肿瘤细胞中转染表达4 - 1bbl,并研究4 - 1bbl在调节淋巴细胞功能活性及抗肿瘤方面的作用和机制。
Objective: To express 4-1bbl in non-immunocytes and non-tumor cells and investigate the role of 4-1bbl in regulation of lymphocyte activity and antitumor effect.
此外,如果能对别种癌细胞的受体活性类型进行描述,这项技术有望应用于所有的实体肿瘤(即非白血病和淋巴癌)。
Moreover, if patterns of receptor-activation for other types of cancers can be characterised, the technique could be applied to all solid tumours (ie, cancers other than leukaemias and lymphomas).
该药物能够准确的将正确的染色体数目导入每一新细胞,产生非整倍体细胞,能够用于治疗由于肿瘤抑制基因突变导致的肿瘤。
Drugs that inhibit accurate delivery of the right number of chromosomes to each new cell, resulting in aneuploidy, would be used to destroy tumors caused by mutations in the tumor suppressors.
滤泡性B细胞淋巴瘤是一种非霍奇金淋巴瘤,肿瘤疫苗是治疗是根据肿瘤细胞的生物学特殊性。
The cancer vaccines rely on a biological quirk of follicular B-cell lymphoma, which is a type of non-Hodgkin's lymphoma.
肿瘤病学家在对可疑或确诊的非小细胞肺癌患者进行分期时要面临多方面因素的考量。
Medical oncologists are faced with multiple factors to consider when staging a patient with suspected or confirmed non-small cell lung cancer (NSCLC).
肺癌死亡率较其他肿瘤要高,只有15%的病人能达到五年存活期,而且非小细胞肺癌占所有肺部肿瘤的75%。
Lung cancer is responsible for more deaths than any other cancer, with only 15% of patients reaching 5-year survival, and non-small cell lung cancer accounts for 75% of all lung cancer.
共有65%的个体经历了恶性肿瘤包括肾母细胞瘤,神经母细胞瘤,非霍奇金淋巴瘤,与中枢神经系统肿瘤的辐射。
A total of 65% had undergone radiation for malignancies including nephroblastoma, neuroblastoma, non-Hodgkin's lymphoma, and tumors of the central nervous system.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂,能阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
类似的相反作用在其他肿瘤抑制因子中也有发现,但H - REV107 - 1的表达与非小细胞肺癌病人存活期的关联还是相当令人震惊。
Similar reverse functions have been identified for other tumor suppressors, but the correlation between H-REV107-1 expression and NSCLC patient survival is quite striking.
通过体外抑瘤试验观察到,非免疫SD大鼠的不同组织透析外液对肿瘤细胞的抑制不是直接杀伤,可能是通过其它机制。
By in vitro experiment, the inhibition by dialysate of non immunized SD rat on tumors was not a direct killing but could be other mechanisms.
目的分析和探讨肿瘤标志物cea、SCC、NSE在非小细胞肺癌临床预诊中的价值。
Objective Analyse and discuss the value of CEA, SCC, NSE in clinical diagnosis of non-small cell carcinoma of lung.
一旦某个异常增生给归类为癌症或肿瘤,也有人将其中细胞的高度非整倍体性,视为癌细胞侵犯性的征兆。
Once an abnormal growth is defined as a cancer, or neoplasm, high cellular aneuploidy is also considered by some to be a sign of aggressiveness.
接下来,医生就能使用放疗和化疗结合的方法来治疗肿瘤,以延长非小细胞型肺癌患者的生存率。
This allowed the doctors to then focus on treating the tumor site in the lungs with a combination of radiation and chemotherapy, helping to extend the survival rates of patients with NSCLC.
KRAS基因突变在恶性肿瘤组织中频发,可预测非小细胞肺癌分子靶向治疗的疗效和预后,针对RAS基因的分子抑制剂研究仍处于初级阶段。
KRAS mutation frequency in tumor tissue, can be predicted non-small cell lung cancer molecular targeted therapy efficacy and prognosis, and molecular inhibitors of RAS genes is still in its infancy.
肿瘤细胞的分子特征可为治疗期间肿瘤基因型的非侵入性系列监测提供一个参考。
Molecular characterization of circulating tumor cells may provide a strategy for noninvasive serial monitoring of tumor genotypes during treatment.
目的探讨肿瘤标记物变化在非小细胞肺癌(NSCLC)患者化疗效果评价中的应用价值。
Objective To discuss the value of application for the changes of tumor markers in evaluation of the effect of chemotherapy on non-small cell lung cancer (NSCLC).
癌症肿瘤细胞组成,被称为恶性肿瘤,细胞非癌的组成被称为良性肿瘤。
Tumors composed of cancer cells are called malignant tumors, and those composed of noncancerous cells are called benign tumors.
这个新研究表明,DNA数量的错误和它在癌细胞里面如何包装-叫做非整倍体-可能影响免疫系统的能力来毁坏肿瘤细胞。
The new study suggests that errors in the quantity of DNA and how it's packaged inside cancer cells - called aneuploidy - might affect the immune system's ability to destroy the cells.
结论口腔鳞癌浸润前沿肿瘤细胞凋亡抑制现象和增殖活性明显高于非前沿部分。
ConclusionThe apoptosis inhibition and proliferation of the tumor cells at the ITF in oral squamous cell carcinoma were more significant than at the non-ITF.
抑制肿瘤新生血管的生成有望降低甚或遏制对非小细胞肺癌化疗的耐药性。
Inhibition of angiogenesis in tumor is expected to reduce or inhibit drug resistance to NSCLC.
但是,经过一段时间癌细胞可以变为雄激素非依赖性,即使在维持这种治疗情况下肿瘤仍然继续生长。
However, over time cancer cells can become "androgen independent," and grow even in the presence of these medications.
结果:我们观察到CD335是在非肿瘤组织的NK细胞中具有高度特异性。
We observed that CD335 was highly specific for NK cells in nonneoplastic tissues.
结论:国人非遗传性肾透明细胞癌中存在VHL基因的突变,且与患者年龄,肿瘤分期、分级无相关性。
The mutations of VHL gene were irrespective of the age and pathological grade and stage of patients.
肌纤维瘤是一种非寻常的肌纤维母细胞增生性肿瘤。
Myofibroma is an uncommon neoplasm characterized by myofibroblastic proliferation.
肾脏良性肿瘤包括:肾血管平滑肌脂肪瘤与肾瘤细胞瘤。这些非癌性肿瘤被认为是良性的,因为它们的生长仅限于肾脏内部。
Benign tumors include: angiomyolipoma and oncocytoma. These non-cancerous tumors are considered benign since they do not have the capacity to grow beyond the kidney to other sites in the body.
目的:探讨CD117在睾丸生殖细胞肿瘤中的表达及其在鉴别睾丸精原细胞瘤和非精原细胞瘤中的价值和生物学意义。
Objective:To evaluate the expression of CD117 in human testicular germ cell tumors and its value in the differential diagnosis of seminoma and nonseminoma.
目的:探讨CD117在睾丸生殖细胞肿瘤中的表达及其在鉴别睾丸精原细胞瘤和非精原细胞瘤中的价值和生物学意义。
Objective:To evaluate the expression of CD117 in human testicular germ cell tumors and its value in the differential diagnosis of seminoma and nonseminoma.
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