该药物能够准确的将正确的染色体数目导入每一新细胞，产生非整倍体细胞，能够用于治疗由于肿瘤抑制基因突变导致的肿瘤。
Drugs that inhibit accurate delivery of the right number of chromosomes to each new cell, resulting in aneuploidy, would be used to destroy tumors caused by mutations in the tumor suppressors.
一旦某个异常增生给归类为癌症或肿瘤，也有人将其中细胞的高度非整倍体性，视为癌细胞侵犯性的征兆。
Once an abnormal growth is defined as a cancer, or neoplasm, high cellular aneuploidy is also considered by some to be a sign of aggressiveness.
非整倍体与肿瘤相关。
这个新研究表明，DNA数量的错误和它在癌细胞里面如何包装-叫做非整倍体-可能影响免疫系统的能力来毁坏肿瘤细胞。
The new study suggests that errors in the quantity of DNA and how it's packaged inside cancer cells - called aneuploidy - might affect the immune system's ability to destroy the cells.
他们发现具有高水平非整倍体的肿瘤患者在治疗后没有活多久。
They saw that patients whose tumours had high levels of aneuploidy didn't live for as long after treatment.
Cleveland教授实验室的研究者建立染色体数目有明显变异的小鼠模型，并分析该非整倍体小鼠模型是否更容易罹患肿瘤。
To find out, researchers in the Cleveland lab created and analyzed mouse models with cells having a highly variable number of chromosomes to discover if such aneuploidy made the mice more tumor-prone.
Cleveland教授实验室的研究者建立染色体数目有明显变异的小鼠模型，并分析该非整倍体小鼠模型是否更容易罹患肿瘤。
To find out, researchers in the Cleveland lab created and analyzed mouse models with cells having a highly variable number of chromosomes to discover if such aneuploidy made the mice more tumor-prone.
应用推荐