本文就染色体基因位点与非综合征性唇腭裂致病机制的关系作一综述。
This review will briefly summarize the relation between gene locus in chromosomes and mechanism of pathopoiesis of NSCLP.
目的:研究雌激素对大鼠附睾上皮细胞非基因组作用及其机制。
Objective: To study estrogen non-genic-group action and its mechanism on rat epididymal cell.
真核生物对维持基因组的稳定性及防止非整倍体的产生,有其一套完整的保护机制,即细胞周期调控、检验点调控以及对损伤DNA的修复。
To ensure genome integrity and prevent aneuploidy, eukaryotes have evolved an integrated protective mechanism, including cell cycle control, checkpoint control, and DNA repair.
目的探讨硬癌、不典型髓样癌和典型髓样癌细胞凋亡非基因调控机制与预后关系。
Objective To study the relationship between mechanism of non-gene regulation apoptosis and prognosis of typical medullary carcinoma, atypical medullary carcinoma and scirrhous carcinoma.
结论EGCG能使RASSF1A基因去甲基化,并上调其非甲基化基因和蛋白的表达水平,这可能是其抗肿瘤的重要机制。
Conclusion Demethylation of RASSF1A and increasing its mRNA and protein induced by EGCG may be one of the mechanisms of its antineoplastic activity.
结论EGCG能使RASSF1A基因去甲基化,并上调其非甲基化基因和蛋白的表达水平,这可能是其抗肿瘤的重要机制。
Conclusion Demethylation of RASSF1A and increasing its mRNA and protein induced by EGCG may be one of the mechanisms of its antineoplastic activity.
应用推荐