他们发现青蒿素和青蒿琥酯是安全的,而且可以迅速清除疟原虫,它们的剂量越高效果越好。
They found that both artemisinin and artesunate were safe and cleared the parasite rapidly, with high doses more effective.
但是,有一些早期证据显示,对青蒿素的耐药性可能也正在缅甸和泰国的边界出现。
However, there is some early evidence that resistance to artemisinins may also be emerging on the Myanmar-Thailand border.
科学家在继续调查青蒿素耐药性具体出现的方式和原因。
Scientists continue to investigate how and why artemisinin resistance specifically emerges.
但是三种抗疟药——青蒿素、青蒿琥酯和蒿甲醚——栓剂的有效性从未进行过比较。
But the three types of antimalarial available in suppository form - artemisinin, artesunate and artemether - have never been compared for effectiveness.
在2009年2月,世卫组织证实在柬埔寨和泰国边界已出现对青蒿素的耐药性。
In February 2009, WHO confirmed that resistance to artemisinin had emerged on the Cambodia-Thailand border.
今天,疟原虫已对仅含青蒿素的抗疟疾药物产生耐药性,世卫组织要求实验室停止对单药疗法的市场营销和销售。
Today, the parasite has become resistant to anti-malarials that contain only artemisinin and WHO has requested laboratories to end the marketing and sale of single-drug treatments.
如同大多数草药一样,青蒿素的含量和效力取决于气候、地理和环境条件。
As with most medicinal herbs, artemisinin's contents and efficacy are subject to climatic, geographical and environmental conditions.
以青蒿素为基础的联合治疗药物要比氯喹和其它常用抗疟药至少昂贵10倍。在许多地区,这些药物由于疟原虫已对它们具有耐药性而不再有效。
ACTs are at least 10 times more costly than chloroquine and other commonly used malaria drugs, which are no longer effective in many regions because the malaria parasite has become resistant to them.
然而,必须使更多的人获得经证实的诸如杀虫剂处理的蚊帐和最近的以青蒿素为基础的复合疗法的干预措施,我们才能对疟疾产生实际的影响。
However, proven interventions such as insecticide-treated nets, and the latest artemisinin-based combination therapies must reach many more people before we can have a real impact on malaria.
世卫组织建议使用含青蒿素副产品和另一种有效抗疟药物的联合化疗。 青蒿素是从青蒿植物中提炼出来的一种物质。
WHO recommends combinations that contain derivatives of artemisinin — a substance extracted from the plant Artemisia annua — along with another effective antimalarial drug.
在巴布亚新几内亚部分地区,青蒿醚加苯芴醇和二氢青蒿素加哌喹分别是治疗小儿恶性疟原虫疟疾和间日疟的最具成本效益的治疗方案。
A+L and DHA+PQ are highly cost-effective regimens for the treatment of paediatric P. falciparum and P. vivax malaria, respectively, in parts of Papua New Guinea.
在经杀虫剂处理的蚊帐和以青蒿素为基础的联合治疗被用于对抗疟疾之前许多年,我们就已经掌握了这些手段有效性的数据。
And we already had data on the effectiveness of insecticide-treated bed nets and ACTs against malaria years before they were implemented.
单一的青蒿素药品,即口服青蒿素单一疗法已于2008年9月起被禁止进口和销售。
It banned the import and sale of separate artemisinin tablets, known as oral artemisinin monotherapy, in September 2008.
自2008年11月以来,在柬埔寨和泰国边界持续努力控制青蒿素耐药性的扩散。
Efforts to contain the spread of artemisinin resistance on the Cambodia-Thailand border have been ongoing since November 2008.
2010年共采购了1.81亿个疗程的以青蒿素为基础的联合疗法,相比2009年的1.58亿和2005年的1100万疗程大大增加了。
In 2010, 181 million courses of artemisinin-based combination therapies (ACTs) were procured, up from 158 million in 2009, and just 11 million in 2005.
目的:观察冬虫夏草(简称虫草)和青蒿素抑制狼疮性肾炎复发的作用。
Objective: To observe the effect of Cordyceps sinensis and artemisinin in preventing recurrence of lupus nephritis (LN).
通过全面改变行为方式以及开展联络、社区动员和宣传活动等,支持遏制和消除耐青蒿素疟原虫;
support the containment and elimination of artemisinin-tolerant parasites through comprehensive behaviour change, communication, community mobilization and advocacy;
青蒿素是从在中国和越南发现的一种叫青蒿的植物中提取出来的。
Artemisinin is made from the sweet wormwood plant found in China and Vietnam.
结果表明,与生理盐水对照组相比,青蒿素及其糖基化衍生物均可有效抑制肿瘤的生长和延长小鼠寿命,毒性实验表明属于低毒类物质。
Compared with normal sodium, the results showed artemisinin and its glycosylated derivates can suppress growth of tumor and increase in life span of mouse.
比较高效液相色谱法(HPLC)和双波长分光光度法对复方双氢青蒿素片中甲氧苄啶含量测定的作用。
Objective To compare the effects of dual-wavelength spectrophotometry and HPLC on the content of trimethoprim(TMP)in Compound Dihydroartemisinin Tablets.
目的:探讨双氢青蒿素哌喹片在柬埔寨马德望省治疗无并发症恶性疟的有效性和安全性。
AIM: To explore the effect and safety of dihydroartemisinin piperaquine(DP) phosphate tablet in treatment of uncomplicated falciparum malaria in battambang of Combodia.
方法:测定不同培养基以及MS培养基中不同营养元素对黄花蒿发根生物量和青蒿素含量的影响。
Methods: the biomass of hairy roots and artemisinin content were determined in different media and the MS medium with different nutrient components.
采用静态法研究了该聚合物对青蒿素吸附过程的热力学和动力学特性,对吸附过程进行控制机理判断。
The control mechanism of the adsorption process was also investigated. The experimental results showed that the copolymer possessed excellent adsorption performance for artemisinin.
结论:青蒿素可明显抑制uvb反复照射小鼠皮肤中c -kit和PAR - 2的表达,提示系统性应用青蒿素对UV B致小鼠皮肤光损伤有保护作用。
Conclusion: artemisinin can inhibit UVB-induced skin c-KIT and PAR-2 expression, which indicates that systemic use of artemisinin may prevent the damage of ultraviolet.
本文的目的是对抗疟药青蒿素的经皮给药进行系统设计和确定青蒿素贴剂的制备工艺。
The purpose of this study was to investigate a transdermal delivery system of antimalarial drug: artemisinin.
本文的目的是对抗疟药青蒿素的经皮给药进行系统设计和确定青蒿素贴剂的制备工艺。
The purpose of this study was to investigate a transdermal delivery system of antimalarial drug: artemisinin.
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