那天，在马里兰州一个自助洗衣店发现了格雷和德雷帕。
That day, both Gray and Draper were discovered at a laundromat in Maryland.
这并不是推荐人们服用雷帕霉素。
雷帕霉素是一种大环内酯类抗生素。
但是，雷帕霉素并不理想。
目的探索雷帕霉素在慢性移植物抗宿主病治疗中的作用。
Objective To explore the effect of rapamycin in treatment of refractory chronic graft-versus-host-disease(cGVHD).
这种叫雷帕霉素的药最先是在复活节岛的一种细菌中找到的。
The drug, called rapamycin, was originally found in bacteria from Easter Island.
但是新的研究表明雷帕霉素仍然是一个有效的研究衰老的工具。
But the new study shows that rapamycin is still a useful tool for investigating aging.
但是，早些时候的人体试验显示，雷帕霉素有很严重的副作用。
Earlier human trials have shown, however, that rapamycin can have serious side effects.
目的评价雷帕霉素涂层支架在冠状动脉分叉病变中的临床疗效。
Objective To evaluate the clinic effect of CYPHERTM (rapamycin) stent in treatment of bifurcation coronary artery lesion.
尚不清楚，这些问题是否会抵制雷帕霉素可能提供延长生命的益处。
It's unclear whether these problems would counteract any longevity benefit that rapamycin might provide in humans.
以前对雷帕霉素的研究为其也许可以把人的寿命延长十几岁提供了线索。
Previous research on rapamycin has hinted that it may have the power to extend human lifespan by more than a decade.
即便如此，因为雷帕霉素抑制了免疫系统，它对帕金森症患者有负面作用。
However, because rapamycin depresses the immune system, it would have serious side effects for people with Parkinson's.
雷帕霉素是用一种土壤细菌做成的，能将酵母、苍蝇和蠕虫的寿命延长约25%。
Made by a type of soil bacterium, rapamycin has extended the life spans of yeast, flies and worms by about 25 percent.
制药公司也会明智地去寻找与一些药物，这些药物作用与雷帕霉素所作用的生物途径相同。
Pharmaceutical companies would also be wise to hunt for drugs that act on the same biological pathway as rapamycin.
而雷帕霉素和FK506作用受体相同，结构相似，可能会对肾病大鼠产生相似的影响。
Rapamycin and FK506 had the same receptor and similar structure. Objective:To investigate effects of rapamycin on adriamycin induced nephrotic syndrome in rats.
《广告狂人》第四季里，唐。德雷帕就是在此和贝瑟尼谈情说爱的(这让贝蒂伤心不已)。
Don Draper romanced Bethany at Barbetta (much to Betty's dismay) in Season Four of Mad Men.
斯特朗及其同事最近发现，更多的人清楚认为雷帕霉素靶蛋白通道在各个物种间间重要性。
But the new finding by Strong and his colleagues "more clearly identifies the [target of rapamycin] pathway as important across species."
应用她的实验室开发的一种基因工程小鼠，一种名为雷帕霉素的现有药物已经开始临床前研究。
Using the genetically engineered mice her lab developed, one preclinical study is already under way, testing an existing drug called Rapamycin.
至少在患者通常所用的剂量下，雷帕霉素非常容易令其受感染，并且它也有其他方面不好的副作用。
Rapamycin leaves users susceptible toinfection — at least in the doses typically used today — and has otherharmful side effects too.
健康的变老将是一些用在人类身上试验的，类似雷帕霉素药物的尺度，Kaeberlein说到。
Healthy ageing will also be the metric by which medicines like rapamycin are tested against in humans, says Kaeberlein.
但甚至小鼠试验，白藜芦醇也尚未证实像雷帕霉素这么有效，针对一个基因来控制细胞的生长和分化。
But at least in mice, even resveratrol hasn't proven as powerful as rapamycin, which targets a gene that's central to the regulation of cell growth and development.
雷帕霉素会抑制免疫系统的活动，可能因此造成感染和死亡的风险，在这方面已经有过严重的前车之鉴。
Rapamycin suppresses the immune system and carries strong warnings about the resulting risk of infections and death.
目的比较雷帕霉素洗脱支架术与冠状动脉旁路移植术(CABG)治疗多支冠状动脉病变的临床疗效。
Objective To compare the clinical effects of rapamycin-eluting stent implantation and coronary artery bypass grafting (CABG) in treatment of the patients with multi-vessel coronary disease.
有些研究者说，仅仅为了延缓衰老而在健康的人身上试验雷帕霉素或其他任何药物，都会引起严重担忧。
And some researchers say there would be serious concerns in testing rapamycin, or any drug, in healthy people just to slow aging.
与雷帕霉素研究一起发布的一篇评论警告称，由于可能出现致命的副作用，不可服用雷帕霉素来延长寿命。
A commentary released with the rapamycin study strongly cautioned against taking the drug to prolong life because of potentially deadly side effects.
方法64例冠状动脉分叉病变患者随机分为两组，分别植入雷帕霉素涂层支架及普通支架，每组32例。
Methods 64 patients with bifurcation coronary artery lesion were randomly divided into rapamycin stent group and ordinary stent group, 32 cases in each group.
目的研究雷帕霉素对小鼠t淋巴细胞体外的增殖、白细胞介素2 (IL - 2)表达及细胞周期的影响。
Objective To investigate the effects of rapamycin on proliferation, levels of interleukin-2 (IL-2) and cell-cycle of mouse t lymphocytes in vitro.
科学家们可能还没发现那种不老药，但一种叫雷帕霉素的药物，已用来抑制器官移植受体的免疫系统，很接近。
Scientists probably haven't stumbled on that drug yet, but a drug called rapamycin, already used to suppress the immune systems of organ transplant recipients, comes close.
他提到免疫反应、细胞分解与糖代谢是当前的研究热点区域，他自己的实验室计划研究雷帕霉素对干细胞的作用。
He mentioned immune response, cellular breakdown and glucose metabolism as immediate areas of research focus, and in his own laboratory plans to study rapamycin's effects on stem cells.
对雷帕霉素的免疫抑制机理及发酵、纯化、检测方法、应用等方面进行了简述，以期为雷帕霉素的研究提供参考。
This paper introduces immunosuppressive mechanism of rapamycin and fermentation, purification, detection methods, applications, and provide reference for the future research.
应用推荐