粉防己碱的作用机理目前尚不清楚,有待进一步探讨。
The mechanism of action for tetrandrine is obscure at present and needs to be studied further.
目的了解粉防己碱对瘢痕成纤维细胞的超微结构的影响。
Objective To investigate the effect of tetrandrine on the ultrastructure of scar fibroblasts.
目的测定防己黄芪颗粒剂中防己诺林碱、粉防己碱的含量。
OBJECTIVE To determine the content of fangchinoline and tetrandrine in Fangji Huangqi Granule.
目的探讨粉防己碱在急性缺血性肾损伤中的保护性作用机制。
Objective To elucidate the protective mechanism of tetrandrine on acute ischemic renal injury.
结论:粉防己碱抑制培养的牛主动脉内皮细胞内向整流钾电流。
CONCLUSION: Tet inhibited inward rectifying potassium current in cultured bovine aortic endothelial cells.
结果:粉防己碱能明显增加脑血流量,减少钙积累,减轻脑水肿。
RESULTS: Tet could increase cerebral blood flow (CBF), reduce Ca accumulation and decrease cerebral edema.
犤目的犦研究含粉防己碱生物材料对体外培养关节软骨细胞的影响。
To investigate the influence of Radix Stephaniae Tetradr ae (tetrandrine) -contained biomaterials on chondrocytes in vitro.
结论粉防己碱在抗肿瘤方面具有多种药理作用,具有广泛的开发前景。
ConclusionTetrandrine has various pharmacological actions and has a fine prospect in exploitation.
目的:探讨粉防己碱在急性缺血性肾损伤中的作用及与细胞凋亡的关系。
Aim: to elucidate the effect of tetrandrine on acute ischemic renal injury and the relation between tetrandrine and apoptosis.
目的综述近年来粉防己碱抗肿瘤药理研究的最新进展,为其深入研究和开发提供。
ObjectiveTo provide references for the further research and exploitation of Tetrandrine, we expatiate the progress in pharmacological effects on anti - tumor of Tetrandrine in recent years.
本发明公开了一种汉防己碱的用途,用于制备抑制趋化因子表达的组合物以及防治肝损伤。
The invention discloses an application of tetrandrine, which is used to prepare combined substances for inhibiting the expressions of chemokines and to control liver injury.
粉防己碱与BSA相互作用的同步荧光光谱表明, 二者的结合对BSA构象产生了影响。
Results of synchronous fluorescence spectrum showed that the binding could cause conformational changes of BSA.
目的:研究粉防己碱与长春新碱合用能否逆转人乳腺癌M CF 7多药耐药细胞的抗凋亡作用。
Objective: to study whether the anti-apoptotic action is reversed by tetrandrine in a combination with vincristine in human breast carcinoma MCF-7 multidrug-resistant cells.
结论:急性缺血性肾损伤时,中药粉防己碱能够调节肾小管上皮细胞的凋亡水平,以减轻肾组织的损伤。
Conclusion: Tetrandrine can adjust the level of apoptosis in renal tubular epithelial and alleviate renal tissular injury.
目的通过测定血清及胰腺组织炎性细胞因子含量,研究粉防己碱治疗大鼠急性出血坏死性胰腺炎的机制。
OBJECTIVE to investigate tetrandrine mechanism for the treatment of acute hemorrhagic necrotizing pancreatitis in rats by measuring inflammatory cytokines content in plasma and pancreatic tissue.
结果表明:粉防己碱能逆转人早幼粒白血病HL60耐药细胞对三尖杉酯碱的耐药性,值得临床上进一步研究。
The results demonstrated that tetrandrine can reverse the harringtonine resistance in the human promyelocytic leukemia HL60 cells and will be worthful for further clinical research.
结论粉防己碱因其钙拮抗作用,在降低血压、逆转左室肥厚的同时,可使细胞膜钠泵活性、线粒体钙泵活性恢复。
CONCLUSION Tetrandrine, as a calcium channel blockers, can reverse LVH induced by RH and elevate the cardiomyocytic membrane sodium pump and mitochondrial calcium pump activities.
实验结果表明粉防己碱可部分逆转肾血管性高血压所致的大鼠左心室肥厚,降低心肌胶原含量,升高肌球蛋白ATP酶活性。
The results suggest that Tet or Ena partially reduce the hydroxyproline content and elevate myosin ATPase activity of hypertrophied myocardium in renovascular hypertensive rats.
实验结果表明粉防己碱可部分逆转肾血管性高血压所致的大鼠左心室肥厚,降低心肌胶原含量,升高肌球蛋白ATP酶活性。
The results suggest that Tet or Ena partially reduce the hydroxyproline content and elevate myosin ATPase activity of hypertrophied myocardium in renovascular hypertensive rats.
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