他还补充说锌指核酸酶可能对一些基因具有不可预知的作用。
He adds that the zinc finger nucleases could have unpredictable effects on several genes.
他们在使烟草细胞接触锌指核酸酶之外,也添加了可增强抗除草剂特性的基因片段。
When they exposed tobacco cells to the zinc finger nucleases, they also added a version of that gene that enhances herbicide resistance.
锌指核酸酶被设计识别基因组特定DNA序列,之后对其进行酶切,进而删除或替换这段序列。
Zinc-finger nucleases are enzymes that can be designed to find specific DNA sequences in the genome and cut them out, deleting those sequences or swapping one gene for another.
目前正对HIV感染者进行锌指核酸酶临床实验,利用这种酶删除一段使病毒进入免疫细胞的基因。
Clinical trials are underway in HIV patients of zinc-finger nucleases that remove a gene that allows the virus to enter immune cells.
锌指核酸酶是一种人工制做限制性内切酶,通过将锌指DNA结合区与限制性内切酶的DNA切割区融合获得。
Zinc finger nucleases (ZFNs) are artificial restriction enzymes made by fusing an engineered zinc finger DNA-binding domain to the DNA cleavage domain of a restriction enzyme.
过去研究人员通过定位这种酶在基因组中的结合位点,之后检测这些序列是否受损的方法来寻找锌指核酸酶的错误。
In the past, researchers have looked for zinc-finger nuclease errors by assaying where in the genome the enzymes might bind, and checking to see whether those sequences were broken.
通常附着在核酸酶上的锌指,称作ZFNs,它负责切断dna的两条链。
Zinc fingers are usually attached to enzymes called nucleases, dubbed ZFNs, which cut both strands of DNA.
我们可以通过对锌指的设计来靶向单个(特定的)基因,与此同时,核酸酶的存在将破坏该基因。
The zinc-finger design allows us to target a single gene, while the nuclease disrupts the gene.
通过将几个锌指出串联在一起,再加入一个切割dna的核酸酶,研究人员们能够精确地导向将被切割的特异性基因。
Bystringing together several zinc fingers and adding a DNA-cleaving nuclease, researchers can precisely target specific genes to be cut.
锌指蛋白载有一种核酸酶,可以与基因黏附,并使基因永久开启或闭合。
Zinc finger protein contains a DNA enzyme, with the adhesion genes, and genes permanently open or closed.
锌指蛋白载有一种核酸酶,可以与基因黏附,并使基因永久开启或闭合。
Zinc finger protein contains a DNA enzyme, with the adhesion genes, and genes permanently open or closed.
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