高风险状态包括：哮喘，镰状红细胞贫血，艾滋病毒感染，慢性心脏疾病，等等。
High risk conditions included asthma, sickle cell disease, HIV infection, and chronic cardiac disease, among others.
随着镰珠蛋白中氧的去除，红细胞变形成镰状，红细胞膜受到破坏，破裂的可能性增加，从而导致贫血。
With the removal of oxygen from sickle hemoglobin, the red blood cell deforms into a sickled shape. This sickling damages the RBC membrane and increases the likelihood of rupture and anemia.
随着镰珠蛋白中氧的去除，红细胞变形成镰状，红细胞膜受到破坏，破裂的可能性增加，从而导致贫血。
With the removal of oxygen from sickle hemoglobin, the red blood cell deforms into a sickled shape. This sickling damages the RBC membrane and increases the likelihood of rupture and anemia.
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