通过一种病毒把这些重编程因子的混合物引入细胞中,这些细胞发生了变化并在实验室中发育成了胚胎样干细胞群。
After the cocktail of reprogramming factors had been introduced into the cells via a virus, the cells changed and developed in the laboratory into colonies of embryonic-like stem cells.
本文主要从转录因子、表观遗传和信号转导等角度,介绍了细胞重编程分子机制研究方面的进展和未来的方向。
In the present paper we review the role and molecular mechanism of transcription factors, epigenetic regulation and cell signaling in cell reprogramming.
强制表达几个转录因子可以使体细胞重编程为诱导的多潜能干细胞(iPS cells)。
Somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by enforced expression of transcription factors.
对这些转录因子作用机制的了解,有助于细胞重编程分子机制的进一步阐明。
Researching the mechanism of action of these transcription factors is beneficial to the further explanation of the molecular mechanism of the cell reprogramming.
我们的结果为基于iPS因子的重编程过程提供了新的范例,就是这种方法经过改进后能够成为转分化的综合平台。
Our results provide a unique paradigm for iPSC-factor-based reprogramming by demonstrating that it can be readily modified to serve as a general platform for transdifferentiation.
我们的结果为基于iPS因子的重编程过程提供了新的范例,就是这种方法经过改进后能够成为转分化的综合平台。
Our results provide a unique paradigm for iPSC-factor-based reprogramming by demonstrating that it can be readily modified to serve as a general platform for transdifferentiation.
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