这项研究同样证实将非诺贝特加入辛伐他汀不会引起任何肌病(肌肉病变)，静脉血栓或胰脏炎等多余危害。
The study also confirmed that adding fenofibrate to simvastatin did not result in any excess risk of myopathy (muscle problems), venous thrombosis or pancreatitis.
疗效是通过将非诺贝特加入辛伐他汀里取得的。
目的：探讨早期应用辛伐他汀对急性冠脉综合征患者的血脂和C反应蛋白影响。
Objective To observe the influence of simvastatin on blood lipid and Creactive protein in patients with acute coronary syndrome.
当辛伐他汀（特别是大剂量）与某些药物联合服用时，也会增加肌病的风险。
The risk of myopathy is also increased when simvastatin, especially at the higher doses, is used with certain drugs (see Simvastatin Dose Limitations below).
对于医生而言，在决定使用辛伐他汀时，需要考虑辛伐他汀相对于其他降胆固醇治疗的潜在风险和已知获益。
It is important for healthcare professionals to consider the potential risks and known benefits of simvastatin compared to other cholesterol-lowering therapies when deciding to use simvastatin.
目的探讨辛伐他汀滴丸的体外溶出速率。
OBJECTIVE To study the dissolution rate in vitro of simvastatin pills.
目的了解辛伐他汀的副作用，提倡合理用药。
Objective: To understand the adverse effects of simvastatin and promote rational medication.
SEARCH同时包括患者服用辛伐他汀出现肌肉损伤的数据。
SEARCH also included data on muscle injury in patients taking simvastatin.
这些限制适用于所有使用辛伐他汀的患者。
目的：研究辛伐他汀对大鼠成骨细胞增殖和分化功能的影响，探讨其刺激成骨的作用机制。
Objective: to study the effect of simvastatin on osteoblast proliferation and differentiation and to explore the mechanism of stimulation of bone formation by simvastatin.
作为单一成分出售的辛伐他汀是非专利药，商品名为舒降之。
Simvastatin is sold as a single-ingredient generic medication and as the brand-name Zocor.
目的观察在原发高脂血症合并急性冠脉综合征早期应用辛伐他汀对降低血脂的疗效及缺血事件发生的影响。
Objective Observe the blood lipid-reducing efficacy of the simvastatin on earlier stage of primary hyperlipaemia and acute coronary syndrome and the affection of ischemia event.
结论辛伐他汀治疗16周可以通过降低血管阻力增加血流量改善脑血管供血状态。
Conclusions Simvastatin, after 16 weeks of treatment, can be lower vascular obstruction, increase blood flow, and thus improve brain blood supply.
目的探讨辛伐他汀对颈动脉内膜-中膜厚度及颈动脉粥样硬化斑块的影响。
Objective To investigate the influences of simvastatin on carotid artery Intima-media thickness (IMT) and carotid atherosclerotic plaque.
目的：探明辛伐他汀在不稳定心绞痛治疗中的有益作用。
Objective: To verify the beneficial effect of simvastatin in the treatment of the unstable angina.
目的：探索辛伐他汀对糖尿病肾病高脂血症降血脂疗效和保护肾功能的作用。
AIM: To probe the efficacy of simvastatin for lowering lipidemia in diabetic nephropathy with hyperlipidemia and protecting renal function.
辛伐他汀治疗后肱动脉内径和肱动脉对硝酸甘油的反应均无显著改变。
There was no significant change of vasodilation responding to nitroglycerin and brachial diameter in all groups after simvastatin therapy.
结论辛伐他汀能够抑制血清诱导的心肌细胞肥大，升高pten表达水平可能是其分子生物学机制之一。
Conclusion Simvastatin can inhibit the hypertrophy of cultured rat cardiac myocytes induced by serum, the mechanism of which might be related with the increase of PTEN expression.
结论辛伐他汀与罗格列酮均能降低血脂，并通过降低巨噬细胞CD 40和CD 40l表达发挥抗动脉粥样硬化作用。
Conclusion Simvastatin and rosiglitazone can decrease serum level of lipids and exert anti-atherosclerotic effect by reducing the expression of CD40 and CD40L.
结论辛伐他汀可以降低糖尿病大鼠肾肥大指数，对糖尿病肾脏病变有保护作用。
Conclusion Simvastatin can reduce the kidney hypertrophy index in the diabetic rats and it has renal protective effect on the diabetic rats.
结论：辛伐他汀降血脂同时具有降蛋白尿和保护肾功能作用。
CONCLUSION: Simvastatin can decrease lipidemia, associated to the proteinuria decrease and the protection of renal function.
结论：辛伐他汀促进骨髓基质细胞的分化，提高其矿化能力，有助于骨质疏松症的防治。
Conclusion: We confirmed that simvastatin promote differentiation and capacity of mineralization of BMSC and contribute to the prevention and treatment of osteoporosis.
前言：目的：探讨影响辛伐他汀降脂疗效的临床因素。
Objective: To study the effects on lipid - lowing therapy of simvastatin.
辛伐他汀和胞二磷胆碱可减轻新生大鼠hibd后脑组织损害。
Both simvastatin and CDPC can relieve the damages of the brain in rats HIBD.
结论：辛伐他汀在不稳定心绞痛治疗中，起着肯定的有益作用，并且早期应用可能即获益。
Conclusion: Simvastatin reveals the definite beneficial effect in treating the unstable angina and may get it in the early use.
目的探讨辛伐他汀调脂治疗对稳定劳力型心绞痛合并高胆固醇血症患者运动诱发心肌缺血的影响。
Objective to investigate the effects of simvastatin on myocardial ischemia induced by exercise testing in patients with stable exertional angina pectoris and hypercholesterolemia.
结论辛伐他汀低剂量维持治疗，患者耐受性好，疗效确切，能保持血脂水平持续达标。
Conclusions Patients have a good tolerance, good effects and can keep continuous qualified serum lipid level after maintaining treatment with low dosage of simvastatin.
目的：探讨急性冠脉综合征(ACS)患者早期应用辛伐他汀后血管内皮功能的变化及其临床意义。
Objective: to observe the effects of early simvastatin intervention on endothelial vasodilator function in patients with acute coronary syndrome (ACS).
目的探讨辛伐他汀联合非诺贝特治疗混合性高脂血症的价值。
Objective To discuss the val ue of simvastatin plus fenofibrate for the treatment of mixed hyperlipemia.
目的探讨辛伐他汀联合非诺贝特治疗混合性高脂血症的价值。
Objective To discuss the val ue of simvastatin plus fenofibrate for the treatment of mixed hyperlipemia.
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