PSD3已经证实为肿瘤转移抑制基因。
"PSD3 has been shown to be a metastasis suppressor gene, " said Dr. Field.
BRMS1是2000年在乳腺癌细胞中发现的癌转移抑制基因。
BRMS1 is a tumor metastasis suppressor gene discovered in breast carcinoma cells in 2000.
转移抑制基因是一类只抑制癌细胞的转移但不影响肿瘤发生和生长的基因。
Tumor metastasis suppressor genes is a kind of genes that only suppresses tumor metastasis without affecting tumorigenesis and tumor growth.
癌转移抑制基因是一类只抑制癌细胞的转移而不影响肿瘤的发生与生长的基因。
Tumor metastasis suppressor gene is a kind of genes that only suppresses metastasis without affecting tumorigenicity and tumor growth.
目的：在肿瘤转移过程的研究中，许多证据已经证实了肿瘤转移抑制基因的重要性。
Purpose: Ample evidence supports an important role of tumor metastasis suppressor genes in cancer metastatic processes.
近来对新发现的肿瘤转移抑制基因NM 23和抑癌基因pten引起了人们极大关注。
Recently, the new discovered NM23 gene (a tumor metastasis suppressor gene) and PTEN gene (a tumor suppressor gene) cause people's attention extensively.
目的综述乳腺癌转移抑制基因1（BRMS1）在抑制乳腺癌转移中的作用机理研究进展。
Objective To review the recent studies on the suppressing function of breast cancer metastasis suppressor 1 (BRMS1) in breast cancer metastasis.
肿瘤转移抑制基因能抑制肿瘤细胞的转移，由于肿瘤转移抑制基因的突变或缺失，从而导致肿瘤的浸润和转移。
Tumor metastasis suppressor gene can inhibit the metastasis of tumor cells, mutations or deletions of this kind of genes can lead to tumor invasion and metastasis.
结论：外源性CAR基因的导入可以增强卵巢癌细胞SKOV3间的粘附性，从而抑制肿瘤细胞的侵袭转移表型。
CONCLUSION: Transfected CAR gene may enhance the adhesion ability of ovarian cancer SKOV3 cells, therefore, inhibit the malignant metastatic phenotype of SKOV3 cells.
本文主要就组蛋白乙酰转移酶调节基因转录以及组蛋白去乙酰化酶抑制剂促进记忆形成的作用机理进行综述。
In this paper, we reviewed the mechanisms on histone acetyltransferases regulating gene transcription and histone deacetylase inhibitors promoting memory formation.
目的探讨反义vegf基因和内皮抑素基因联合转染在抑制肿瘤血管生成和肿瘤生长转移中的作用。
Objective to explore the co operative inhibitory effect of antisense VEGF gene and endostatin gene transfection on tumor angiogenesis, tumor growth and metastasis of lung cancer.
本研究旨在通过探讨KAI1基因对具有高转移潜能的人肝癌细胞株MHCC97-H粘附作用的影响，揭示其转移抑制的分子生物学机制。
This study was to explore the effect of KAI1 gene on the adhesion of hepatocellular carcinoma cell line MHCC97-H with high metastatic potential, and to find the possible mechanism.
TGF配体虽然在早期肿瘤中作为肿瘤抑制基因发挥作用，但其在进展期肿瘤中却变成有效的促转移因子。
TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
SIPA1在HCC中发挥肿瘤抑制基因的作用，且对抑制HCC的复发转移有重要作用。
SIPA1 probably inhibits the metastasis and recurrence of HCC as a tumor suppressor gene.
结论外源性pten抑癌基因对高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭具有抑制作用。
Conclusion the exogenous wild-type PTEN gene has significant effects of anti-adhesion, anti-migration, and anti-invasion on the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
结论外源性pten抑癌基因对高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭具有抑制作用。
Conclusion the exogenous wild-type PTEN gene has significant effects of anti-adhesion, anti-migration, and anti-invasion on the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
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