在2002年，他就得出了一个能预测癌症演化和扩散方式的方程组，比如说染色体何时开始变得不稳定，使得癌细胞在转移中发生变异。
In 2002 he worked out equations that can predict the way cancer evolves and spreads, such as when mutations emerge in a metastasis and chromosomes become unstable.
在UCLA琼森癌症研究中心和其他地方的临床试验中，一种试验药物，PLX4021，对BRAF基因变异的黑素瘤转移病人的效果很好。
In a clinical trial at UCLA's Jonsson Cancer Center and other locations, patients with BRAF-mutated metastatic melanoma have been responding very well to an experimental drug, PLX4032.
研究表明，CD44拼接变异体的表达，特别是CD 44v6的表达与肿瘤细胞的生长、浸润、转移及预后密切相关。
It is well elucidated that the expression of CD44 Splice Variants (CD44V), particularly CD44V6, is closely related to tumors growth, infiltration, metastasis and prognosis.
通过分析血浆中的变异或变异类型，研究者并未观察到疾病转移方式的差异。
The researchers did not observe any differences in disease metastatic patterns, according to the presence of mutations in serum or the type of mutation.
通过分析血浆中的变异或变异类型，研究者并未观察到疾病转移方式的差异。
The researchers did not observe any differences in disease metastatic patterns, according to the presence of mutations in serum or the type of mutation.
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