使用趋化作用分析来证实这些趋化因子受体的功能性。
Chemotaxis assays were used to verify functionality of these chemokine receptors.
本文就HIV-1与趋化因子受体的研究进展情况作一综述。
The research progress of HIV-1 and chemokine receptor was introduced in the …
趋化因子CCL21是趋化因子受体(CCR)7的一个配体。
趋化因子受体和它们的配体在粒细胞组织特异性定位中起重要作用。
Chemokine receptors and their ligands play an important role in tissue-specific homing of leukocytes.
目的：探讨趋化因子受体CXCR4表达水平对人肺癌细胞转移潜能的影响。
Objective: to study the effect of the expression levels of Chemokine receptor CXCR4 on the metastatic potential of human lung cancer.
目的：探讨趋化因子受体CCR7在不同类型肺癌组织中的表达及其临床意义。
AIM: to investigate the expression of CC chemokine receptor 7 (CCR7) in different types of lung carcinoma and its clinical significance.
这个实验表明，趋化因子受体CXCR4基因在扁桃体细胞中比在胶状样本中活跃11倍。
This experiment revealed that the CXCR4 gene was 11 times more active in the tonsils than in the gum samples.
目的研究细胞趋化因子受体5（CCR5）在乙型病毒性肝炎（HB）免疫发病机制中的作用。
Objective To investigate the role of CC chemokine receptor 5(CCR5) in the immunological pathogenesis of hepatitis B(HB). ?
全文就新近发现的趋化因子受体CCR7及其配体CCL21和CCL19的研究进展作一综述。
The aim of this article is to review recent development of CCR7, a newly identified chemokine receptor, and its ligand CCL21and CCL19.
该基因编码的一种蛋白质，也被称为趋化因子受体CXCR4，同样有助于艾滋病毒感染免疫细胞。
The gene codes for a protein, also called CXCR4, that also helps HIV infect immune cells.
其在多种肿瘤细胞和肿瘤间质细胞膜上有功能性表达，趋化因子受体与肿瘤多种生物学行为密切相关。
These functional recepters can be expressed in kinds of tumor cells and stromal cells and are closely correlated with the biological behavior of tumors.
趋化因子受体CCR5是HIV?1 进入靶细胞的辅助受体，因而成为开发抗艾滋病药物的新靶点。
CCR5, one of the coreceptors of HIV?1, is a new target of anti-HIV therapy.
在体外培养基中，趋化因子受体的表达即趋化运动的能力和粘附分子的表达受IL2和IL4的调节。
The expression of chemokine receptors, the chemotactic capacities, and adhesion molecule expression was modulated by withdrawal of IL 2 and IL 4 from the culture medium.
由于其在肿瘤细胞器官选择性转移中的重要作用，趋化因子受体有希望成为肿瘤治疗的靶标并具有预后价值。
Chemokine receptors may become the hopeful targets in tumor therapy and have merits of prognosis because of their critical roles in tumor metastasis to specific organs.
许多研究表明：趋化因子受体拮抗剂对各种与趋化因子相关的疾病具有较好的疗效，有些药物已经进入临床试验中。
It has been proved that chemokine receptor antagonists have ideal curative effects on the diseases related to chemokines, and some drugs have entered the clinical tests.
目的探讨趋化因子受体家族中CC趋化因子受体7（CCR7）在寻常型银屑病患者皮损及外周血T细胞上的表达情况。
Objective To investigate different significance and expression of the CC chemokine receptor CCR7 of T cells from the peripheral blood or skin models in patients with psoriasis vulgaris.
近年来，HIV - 1在借助趋化因子受体(C CR 5,CXCR4)感染免疫细胞方面的研究引起了广泛关注。
In the recent years, the research of HIV-1 infecting immunocytes by chemokine receptor CCR5 and CXCR4 was caused more attention.
应用四色荧光活化流式细胞术(FACS)检测CD 34 +细胞其粘附分子及趋化因子受体CXCR -4的表达谱。
Four color fluorescence activated cell sorting (FACS) analysis was applied to detect the expression profiles of adhesion molecules and chemokine receptor CXCR 4 on CD34 bright cells.
目的：构建趋化因子受体c CR 5,CXCR4双靶区反义rna重组载体并获取重组腺病毒以用于抗hiv1基因治疗的研究。
AIM: to construct the recombinant adenoviral vector carrying antisense RNA to chemokine receptors CCR5 and CXCR4 and to obtain recombinant adenovirus, which will be used to resist HIV 1 infection.
趋化因子及其受体是肿瘤细胞生物学行为的重要调节因素。
Chemokines and chemokine receptors are important regulatory factors in tumor behaviors.
结论：趋化因子CXCL12、受体CXCR4和CXCL12—CXCR4生物学轴在肿瘤转移中发挥着重要的作用。
Conclusion: The chemokine factor CXCL12, its receptor CXCR4 and biological axis of CXCL12-CXCR4 play important roles in tumor metastasis.
结果：研究表明许多肿瘤细胞表达趋化因子CXCL12和受体CXCR4，与肿瘤细胞的迁移与转移有密切关系。
Results: Researchs indicated that various tumor cells expressed chemotactic factor CXCL12 and its receptor CXCR4, which was closely related to migration and metastasis of tumor cells.
它们的这些生物学功能是通过配体与受体结合的方式来发挥的，而CXCR3与CCR5是RA中趋化因子的标志性受体。
All of these biological effects are performed by binding of ligands to receptors. Elsewhere, CXCR3 and CCR5 are mark chemokine receptors in RA.
针对趋化因子及其受体的靶向治疗能减轻炎症损伤，可望成为一种新的炎症性肠病的治疗方法。
Targeted therapy that aims directly at chemokines and their receptors can ameliorate inflammatory damage, and can be a novel therapeutics for inflammatory bowel disease.
在炎症性肠病中，许多趋化因子及其受体表达增加，并在发病机制上起着重要作用。
Many chemokines and their receptors show increased expression in inflammatory bowel disease, which play an important role in the pathogenesis of the disease.
近年来的研究发现，器官特异性表达的趋化因子及癌细胞表达的受体介导的趋化运动在肿瘤的侵袭和转移过程中发挥着重要的作用。
Recent data indicated that chemotaxis, which involves the chemokines expressed at specific organs and their receptors expressed on tumor cells, plays a crucial role in tumor invasion and spreading.
粘附分子和粘附受体在这一过程中起重要作用，多种细胞因子和趋化因子参与了单核细胞募集的调节。
This is called "monocyte recruitment". Adhesive molecules and adhesive receptors take part and play an important role in the process.
粘附分子和粘附受体在这一过程中起重要作用，多种细胞因子和趋化因子参与了单核细胞募集的调节。
This is called "monocyte recruitment". Adhesive molecules and adhesive receptors take part and play an important role in the process.
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