真核生物基因顺式作用元件分为启动子、增强子、沉默子，是调节基因转录的特定DNA序列。
Eukaryotic gene cis-acting element includes the promoter, enhancer, silencer, which are the specific DNA sequences regulating gene transcription.
本文主要就组蛋白乙酰转移酶调节基因转录以及组蛋白去乙酰化酶抑制剂促进记忆形成的作用机理进行综述。
In this paper, we reviewed the mechanisms on histone acetyltransferases regulating gene transcription and histone deacetylase inhibitors promoting memory formation.
经磷酸化活化的丝裂原活化蛋白激酶，可参与多种细胞生命活动，如调节基因转录，诱导细胞凋亡、调节细胞周期等。
The MAPK which activated through phosphorylation involve several cell life activities, just like the control gene transcription, induce cell death, regulate cell circle and so on.
AMPK被激活后在增加骨骼肌对葡萄糖摄取、增强胰岛素敏感性、增加脂肪酸氧化以及调节基因转录等方面发挥重要作用。
Activated-AMPK plays important roles in increasing glucose uptake in skeletal muscle cells, increasing fatty acid oxidation, improving insulin sensitivity and regulating gene transcription.
例如，电路可以模拟出乳糖代谢基因与调节细菌细胞内乳糖代谢基因表达的转录因子之间的互动过程。
For example, circuits can simulate the interactions between genes involved in lactose metabolism and the transcription factors that regulate their expression in bacterial cells.
EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子，它可以EGR响应元素(ER)，调节靶基因的表达(1)。
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).
为了了解LXR如何调节低密度脂蛋白受体，作者研究了LXR靶基因的转录，并确定了一个能编码肌球蛋白互动蛋白的基因，IDOL。
To understand how LXR regulates LDLR, the authors examined transcriptional target genes of LXR and identified a gene that encodes a myosin interacting protein, IDOL.
自然界中有一类名为转录因子的蛋白可调节(升高或者降低)基因的活性，该技术正是基于该机理。
The technique relies on a natural process by which the activity of genes is raised or lowered by proteins called transcription factors.
在真核生物中基因表达的调节主要是在转录水平。
Gene expression in eukaryotes is regulated primarily at the level of transcription.
已有研究表明DNA顺式作用元件与反式作用因子之间的相互作用是染色质重塑和基因转录调节的基础。
Present studies indicate that the interactions between trans-acting factors and corresponding DNA cis-acting elements are the basis of chromatin remodeling and gene transcription regulation.
而那些低表达的基因，功能涉及转录调节、小泡运输、铁代谢、信号转导，以及细胞外基质的组成和生物转化。
The genes with lower expression function in areas such as transcription regulation, vesicular transport, iron metabolism, signal transduction, and extracellular matrix organization and biogenesis.
热激转录因子在调节植物对逆境胁迫应答和热激蛋白基因表达方面起重要作用。
Heat shock transcription factors (HSFs) are important in regulating heat stress response by mediating expression of heat shock protein (HSP) genes in various plant species.
常规的思维认为如果不是基因机构不同，那一定是基因转录蛋白的调节方式不同。
Conventional wisdom has been that if the difference is not the gene content, the difference must be in the way regulation of genes produces their protein products.
PPAR的主要功能是调节基因的转录。
The main function of PPAR is to regulate the transcription of genes.
SITR 1是一种组蛋白脱乙酰基酶，一种能够阻断来自调节基因的转录因子的蛋白质。
SITR1 is a histone deacetylase, a protein that blocks transcription factors from regulating genes.
转录因子低氧诱导因子1（HIF1）已被证明可以调节多个参与代谢活动的基因。
The transcription factor hypoxia-inducible factor 1 (HIF1) has been implicated in regulating many of the genes that are responsible for the metabolic difference.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
据Sarkar的说法，LSF是一种转录因子，这意味着它可以直接调节基因的表达。
According to Sarkar, LSF is a transcription factor, which means it can directly regulate the expression of genes.
LPL活性调节的这种组织特异性主要是由于不同组织lpl基因转录速率不同所决定的。
The tissue-specific changes in LPL activity can be determined by the different rate of LPL gene transcription in different tissue.
IAA蛋白的泛素化降解在生长素反应中发挥关键性作用，ARF和AUX/IAA蛋白相互作用调节生长素响应基因的转录。
The degradation of AUX/IAA protein by ubiquitination plays essential role in auxin response, and the interaction between ARF and AUX/IAA protein regulates the transcription of auxin-response genes.
BRD7被鉴定为一个鼻咽癌密切相关新基因和潜在的核转录调节因子。
BRD7 was identified as a novel gene tightly associated to nasopharyngeal carcinoma (NPC) and also a nuclear transcriptional regulatory factor.
在心肌细胞中，T3结合到细胞核中的甲状腺激素受体，其依次结合靶基因调节区中的甲状腺激素反应元件以调节转录。
In the cardiomyocyte, T3 binds to thyroid hormone receptors in the nucleus, which in turn bind to thyroid hormone response elements in the regulatory regions of target genes to regulate transcription.
这些结果说明opbp1基因可能作为一转录因子来调节烟草耐盐相关的基因。
These results suggested that OPBP1, as a transcription factor is involved in the regulation of salt stress related genes.
激素脱落酸（ABA）参与了植物对逆境适应，调节包括一些转录因子在内的许多逆境响应基因的表达。
The phytohormone abscisic acid (ABA) is involved in the adaptive stress response and regulates expression of many stress-responsive genes, including some transcriptional factors.
真核生物中热激蛋白基因的表达受热激转录因子的调节。
The expression of heat shock protein genes in eukaryotes is regulated by heat shock transcription factor (HSF).
植物同源异型基因及同源异型盒基因是涉及植物个体发育调节的两类重要转录因子编码基因。
Plant homeotic genes and homeobox genes are two types of the important genes encoding transcription factors involved in plant development.
用小分子靶向转录因子以调节特定基因的表达是众所周知难以实现的。
Targeting transcription factors with small molecules to modulate the expression of certain genes has been notoriously difficult to achieve.
以含雌激素反应元件的荧光素酶(ERE -LUC)为报告基因，通过检测荧光素酶活性来确定MDM2是否对ER有转录调节因子的作用。
The effect of MDM2 on the transcriptional activity of er was detected by the reporter gene containing estrogen responsive elements luciferase (ERE-LUC).
HAP1基因编码的一个复杂的转录调节许多基因参与了电子转移反应，是必不可少的厌氧或血红素枯竭条件。
The HAP1 gene encodes a complex transcriptional regulator of many genes involved in electron-transfer reactions and is essential in anaerobic or heme-depleted conditions.
核受体家族的经典作用机制是在其配基存在下结合在靶基因的应答元件上，从而在转录水平上调节基因的表达。
The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.
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