这就引出问题,转录因子是否能直接诱导其它明确的体细胞,而不仅是未分化状态的细胞。
This raised the question of whether transcription factors could directly induce other defined somatic cell fates, and not only an undifferentiated state.
低氧诱导因子1 (HIF - 1)是重要的氧依赖性核转录因子,低氧条件下能上调多个靶基因表达以减少缺氧性损伤。
Hypoxia inducible factor-1 (HIF-1) is a key oxygen-dependent transcription factor that up-regulates many protective genes against hypoxia-induced injury.
在热激基因的转录诱导中,热激因子和热激元件的协同作用是决定性的。
Binding of heat shock factors (HSFs) with heat shock element sequence is critical for the transcriptional induction of heat shock genes.
目的探讨内毒素(LPS)诱导的急性肺损伤(ALI)大鼠肺组织甲状腺转录因子-1(TTF-1)、肺表面活性物质相关蛋白-A(SP-A)表达的变化。
Objective To investigate the change of the expression of TTF-1 and SP-A in lung tissue of ALI rats induced by LPS.
缺氧诱导因子- 1是近几年研究较多的转录因子,它可使肿瘤在生长侵袭过程中适应缺氧应激,也为肿瘤治疗提供了新思路。
Hypoxia-induced factor-1 is a transcription factor which is widely studied in recent years. It helps progressing tumors adapt to hypoxia stress and also provides a new clue for tumor therapy.
强制表达几个转录因子可以使体细胞重编程为诱导的多潜能干细胞(iPS cells)。
Somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by enforced expression of transcription factors.
目的:分析甲基硝基亚硝基胍(MNNG)诱导的共表达蛋白的编码基因启动子区的转录因子结合部位。
AIM: to find out common transcription factor binding sites in the promoter regions of the encoding genes of the co-expressive proteins induced by N-methyl-N '-nitro-n - nitrosoguanidine (MNNG).
DREB是一类和植物脱水条件下的抗逆性反应有关的调节因子蛋白,是可以同时调控多个逆境诱导基因表达的转录因子。
DREB is a kind of regulator protein which is relatived with the resistance under the dehydration condition, and this transcription factor can control the expression of many inducible stress genes.
乏氧诱导因子(HIF)是乏氧应答中起重要作用的转录因子,一直是乏氧研究的焦点。
Hypoxia-inducible factor (HIF) is an important transcriptional factor, which plays crucial role in response to hypoxia.
缺氧诱导因子1(HIF-1)是近年发现的调控细胞低氧适应性变化的重要转录因子。
Hypoxia-inducible factor-1(HIF-1), a newly discovered factor in recent years, is an important transcription factor which can control the cells′adaptive responses to hypoxia.
转录因子低氧诱导因子1(HIF1)已被证明可以调节多个参与代谢活动的基因。
The transcription factor hypoxia-inducible factor 1 (HIF1) has been implicated in regulating many of the genes that are responsible for the metabolic difference.
缺氧诱导因子- 1 (HIF - 1)是由低氧等诱导细胞产生的1种转录因子,能激活许多缺氧反应性基因的表达。
Hypoxia inducible factor-l (HIF-1), which can stimulate expression of hypoxia induced-responsed, is a kind of transcriptive factor.
系-具有辐射诱导特性的转录因子。
目前对这一现象有四种解释:ROS活化核转录因子KB并诱导核转录因子-KB表达,导致细胞凋亡;
At present, the explanations for this phenomenon are: 1) ROS activated nuclear factor-KB and induction of the expression of nuclear factor-KB; 2) mitochondria-mediated cell apoptosis;
目前对这一现象有四种解释:ROS活化核转录因子KB并诱导核转录因子-KB表达,导致细胞凋亡;
At present, the explanations for this phenomenon are: 1) ROS activated nuclear factor-KB and induction of the expression of nuclear factor-KB; 2) mitochondria-mediated cell apoptosis;
应用推荐