问题关键在于找到正确的诱导干细胞分化成心脏细胞,神经细胞,制造胰岛素的细胞或者其他细胞的生长因子的正确方法。
The key lay in finding just the right recipe of growth factors and nutrients to induce a stem cell to become a heart cell, a neuron, an insulin-making cell or something else.
这就引出问题,转录因子是否能直接诱导其它明确的体细胞,而不仅是未分化状态的细胞。
This raised the question of whether transcription factors could directly induce other defined somatic cell fates, and not only an undifferentiated state.
背景资料概要:目前已有不同的生长和分化因子使用于脊柱融合中诱导骨形成。
Summary of Background Data. Different growth and differentiation factors are currently being used for inducing bone formation in spinal fusion.
目的:探讨肝细胞生长因子(HGF)诱导小鼠胚胎干细胞(ESC)体外定向分化为肝细胞的细胞功能表现。
Objective To investigate the role of murine Hepatocyte growth factor(HGF) inducing mouse embryonic stem cells(ESC) in vitro to commitmently differentiate into hepatocyte.
BMP是骨生长的启动因子,能诱导骨髓基质细胞分化为成骨细胞和骨细胞,促进钙化作用,产生钙化的骨基质。
BMP is the start of bone growth factor, can induce bone marrow stromal cells differentiate into bone cells and bone cells, to promote calcification, resulting in calcification of bone matrix.
本文就含有特定生长因子的培养基诱导人脐带MSC和人胎盘MS C定向分化的研究进展作一简要的综述。
The paper makes a brief review on culture medium which contains specific growth factor inducing directed differentiation of human umbilical cord-derived and human placenta-derived MSCs.
目的观察视黄酸对人横纹肌肉瘤细胞的诱导分化作用及对生肌调节因子(MRF)表达的影响。
Objective To study the effects of retinoic acid on the differentiation of human rhabdomyosarcoma cells and on the expression of myogenic regulatory factor (MRF).
背景:现阶段诱导骨髓基质细胞分化成骨的方法大致分为在化学药物作用、细胞因子作用以及转基因作用下的分化等。
BACKGROUND: the methods of inducing the differentiation of bone marrow stromal cells into osteoblasts included the differentiation under chemicals effect, cytokine effect and transgenosis.
目的 :研究三七总甙对NB4细胞促凝活性和组织因子表达及诱导分化作用的影响。
Objective:To investigate the effect of Panax notoginseng saponin (PNS) on procoagulant activity (PCA) and differentiation induction in NB4 cells.
目的:观察多因子联合诱导和分步诱导方案诱导大鼠脂肪组织源性干细胞体外分化为神经元样细胞的可行性。
OBJECTIVE: to explore the feasibility of inducing rat ADSCs into neuron-like cells with a new scheme and medium containing multiple factors.
结论人脐血单核细胞体外经细胞因子诱导分化培养,可生成大量的DC。DC体外可促进T细胞对神经母细胞瘤细胞的杀伤效应。
Conclusions Human cord blood mononuclear cells could be served as a better source of DC, which can promote the capacity of initiating T cell-dependent anti neuroblastoma tumor immune responses.
方法联合应用粒细胞—巨噬细胞集落刺激因子(GMCSF)、白细胞介素4(IL4)诱导培养小鼠脾脏单个核细胞分化为DC,并从形态学、表型及功能方面对其加以检测。
Methods Mononuclear cells isolated from mice spleen were induced into DC by GMCSF and IL4, and then detected with their morphology, phenotype and function.
方法联合应用粒细胞—巨噬细胞集落刺激因子(GMCSF)、白细胞介素4(IL4)诱导培养小鼠脾脏单个核细胞分化为DC,并从形态学、表型及功能方面对其加以检测。
Methods Mononuclear cells isolated from mice spleen were induced into DC by GMCSF and IL4, and then detected with their morphology, phenotype and function.
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