前言: 目的:研究人胚胎卵巢中是否存在褪黑素受体。
Objective: To examine whether the ovary of human embryo expresses the melatonin (MEL) receptor and to explore its molecular characters.
目的证实人外周血白细胞存在褪黑素受体(MR)及建立检测方法。
Objective to verify whether there exist melatonin receptors (MR) in human peripheral leucocytes and to establish the technique of measuring MR.
目的:研究人外周血淋巴细胞褪黑素受体(MR)的基因与蛋白表达的特点。
AIM: to investigate the melatonin receptor (MR) gene and protein expression in the human peripheral blood lymphocytes.
为明确人体胃组织是否存在褪黑素受体(MR),应用放射配体结合法检测人体胃组织MR特异结合量。
To determine whether melatonin receptors (MR) exist in human stomach, specific binding of melatonin receptor in human stomach was measured by radioligand binding assay.
例如,褪黑素受体的阻碍能影响天黑晚的认知能力,那么对于那些夜班工作者和熬夜备考的学生都有所辅佐。
For example, the use of melatonin receptor blockers could improve performance of night-time cognitive tasks, helping people such as night-shift workers or students cramming for exams.
结论:褪黑素延长小鼠睡眠时间的作用与褪黑素3型受体无关,而与GABAA受体关系密切,其作用主要由印防己毒素结合位点介导。
Conclusion: Melatonin does not exhibit its potentiation sleeping time in mice through melatonin 3 receptor. Hypnotic activity of melatonin may be mediated through picrotoxin site on GABAA receptor.
结论:褪黑素延长小鼠睡眠时间的作用与褪黑素3型受体无关,而与GABAA受体关系密切,其作用主要由印防己毒素结合位点介导。
Conclusion: Melatonin does not exhibit its potentiation sleeping time in mice through melatonin 3 receptor. Hypnotic activity of melatonin may be mediated through picrotoxin site on GABAA receptor.
应用推荐