能明显抑制小鼠毛细血管通透性增高和棉球肉芽肿形成。
It can reduce capillary permeability and granuloma formation in mice.
结论体外循环可诱导炎症反应致内皮细胞损伤或激活,并可致血管通透性增高。
Conclusion CPB can induce activation damage of vascular endothelial cell, and increase vascular permeability.
S1P能改善PAF引起的血管通透性增高,其作用与加强内皮细胞间粘附连接,抑制细胞间隙打开有关。
S1P improves the increase in the microvessel permeability caused by PAF, which might be mediated by strengthening adherent junction and inhibiting the formation of endothelial gaps.
采用二甲苯致小鼠耳廓肿胀、甲醛致小鼠足肿胀、冰醋酸致小鼠腹腔微血管通透性增高模子不雅察该药的抗炎作用。
Xylene was used to induce mouse ear swelling, formaldehyde was used to induce mouse foot swelling and ice-acetic acid was used to increase blood capillary leakage in mouse abdominal cavity.
血脑屏障通透性增高是造成血管源性脑水肿和炎症反应等病理学变化的主要环节。
The increase of blood-brain barrier (BBB) permeability is a key link in causing the pathological changes in vasogenic brain edema and inflammatory reaction.
豚鼠急性定量吸烟可引起肺气道阻力明显上升,肺动态顺应性明显下降,还可引起肺气道组织小血管通透性明显增高的反应。
Acute inhalation of cigarette smoke decreases dynamic lung compliance, increases airway resistance and vascular permeability of pulmonary vessels in guinea pigs.
结果(1)肺损伤组各时相点血浆P 选择素、肺组织MPO活性、肺毛细血管通透性均较对照组显著增高(P<0 0 1) ;
Results (1)Plasma P selectin levels, lung MPO, pulmonary capillary permeability at every time points in endotoxin group was much greater than those observed in control group( P< 0 01).
结果(1)肺损伤组各时相点血浆P 选择素、肺组织MPO活性、肺毛细血管通透性均较对照组显著增高(P<0 0 1) ;
Results (1)Plasma P selectin levels, lung MPO, pulmonary capillary permeability at every time points in endotoxin group was much greater than those observed in control group( P< 0 01).
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