我们没有观察到利培酮合用锂盐或丙戊酸钠的不良反应，尽管在丙戊酸钠上血浆浓度峰值增加20%。
No effects of risperidone on lithium or valproate exposure were observed, despite a 20% increase in valproate peak plasma concentration.
结论：CHIP腹腔ddp浓度高，血浆峰值较低，以及高温作用，有利于化疗药物在局部对肿瘤细胞发挥作用，减少肾毒性和全身副作用。
Conclusion: CHIP provides high concentration of DDP in the peritoneal cavity, inducing higher local tumoricidal effect, lower nephric and systemic toxicity.
结论：CHIP腹腔ddp浓度高，血浆峰值较低，以及高温作用，有利于化疗药物在局部对肿瘤细胞发挥作用，减少肾毒性和全身副作用。
Conclusion: CHIP provides high concentration of DDP in the peritoneal cavity, inducing higher local tumoricidal effect, lower nephric and systemic toxicity.
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