遗传突变的视紫红质,光传感蛋白的燃料棒细胞,单是最常见的一种形式的反相和大多数这些突变导致蛋白质错误折叠。
Inherited mutations in rhodopsin, the light sensing protein of rods cells, are the single most common cause of one form of RP and the majority of these mutations cause protein misfolding.
BlueGene/L技术提供了一种强大的方法来研究这些类型的疾病,因为它能够更加经济高效地(和更快地)建模蛋白质折叠和错误折叠的效果。
The Blue Gene/L technology offers a powerful way to study these types of diseases, because it provides a more cost-effective (and faster) way to model the effects of protein folding and misfolding.
学习蛋白质折叠式了解一些神经性能疾病的关键,而这些疾病则是由于某些蛋白质的折叠错误而产生的。
Studying protein folding is key to understanding several neurodegenerative diseases that are a result of the incorrect folding of certain protein strings.
错误折叠之前的蛋白质状态。
其主要作用之一就是识别错误折叠或未折叠蛋白质,并继而纠正这种错误折叠或未折叠。
One of its main actions is to recognize misfolded or unfolded proteins and then correct the misfolding or unfolding.
在很多蛋白质凝聚的疾病中,错误折叠的蛋白自我结合,形成纤维样的凝集体,从而导致脑细胞死亡和老年痴呆。
In many protein aggregation diseases, incorrectly folded proteins self-associate, forming fiber-like aggregates that cause brain cell death and dementia.
近年来研究发现,蛋白质的错误折叠可以形成淀粉样沉积进而导致一些疾病的产生。
In recent years, a number of diseases are believed to be caused by amyloid deposition results from protein misfolding.
这种酶的主要功能是支持确保细胞健康的通路,并降解清理那些错误折叠的或已经完成使命的蛋白质。
The enzyme's chief duty is to support the pathway that ensures that cells remain healthy and clutter free by breaking down proteins that are misfolded or have outlived their usefulness.
这种酶的主要功能是支持确保细胞健康的通路,并降解清理那些错误折叠的或已经完成使命的蛋白质。
The enzyme's chief duty is to support the pathway that ensures that cells remain healthy and clutter free by breaking down proteins that are misfolded or have outlived their usefulness.
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