• 遗传突变视紫红质传感蛋白燃料棒细胞是最常见一种形式相和大多数这些突变导致蛋白质错误折叠

    Inherited mutations in rhodopsin, the light sensing protein of rods cells, are the single most common cause of one form of RP and the majority of these mutations cause protein misfolding.

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  • BlueGene/L技术提供了一种强大的方法研究这些类型疾病因为能够更加经济高效地更快地建模蛋白质折叠错误折叠效果

    The Blue Gene/L technology offers a powerful way to study these types of diseases, because it provides a more cost-effective (and faster) way to model the effects of protein folding and misfolding.

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  • 学习蛋白质折叠了解一些神经性能疾病关键而这些疾病则由于某些蛋白质折叠错误而产生的。

    Studying protein folding is key to understanding several neurodegenerative diseases that are a result of the incorrect folding of certain protein strings.

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  • 错误折叠之前蛋白质状态

    Protein state prior to misfolding.

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  • 主要作用之一就是识别错误折叠折叠蛋白质继而纠正这种错误折叠或未折叠

    One of its main actions is to recognize misfolded or unfolded proteins and then correct the misfolding or unfolding.

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  • 很多蛋白质凝聚疾病中错误折叠蛋白自我结合,形成纤维样的凝集体,从而导致脑细胞死亡老年痴呆

    In many protein aggregation diseases, incorrectly folded proteins self-associate, forming fiber-like aggregates that cause brain cell death and dementia.

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  • 近年研究发现,蛋白质错误折叠可以形成淀粉样沉积进而导致一些疾病的产生。

    In recent years, a number of diseases are believed to be caused by amyloid deposition results from protein misfolding.

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  • 这种主要功能支持确保细胞健康通路降解清理那些错误折叠已经完成使命蛋白质

    The enzyme's chief duty is to support the pathway that ensures that cells remain healthy and clutter free by breaking down proteins that are misfolded or have outlived their usefulness.

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  • 这种主要功能支持确保细胞健康通路降解清理那些错误折叠已经完成使命蛋白质

    The enzyme's chief duty is to support the pathway that ensures that cells remain healthy and clutter free by breaking down proteins that are misfolded or have outlived their usefulness.

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