• 基于BLAST搜索,得到植物丝裂原活化蛋白激酶激酶基因序列

    Based on the result of BLAST search, 7 plant MAP kinase kinase sequences were collected.

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  • 腺苷酸结合蛋白激酶调节亚基一个磷酸化蛋白激酶磷酸化酶激酶

    Cyclic AMP binds to the regulatory subunit of protein kinase A: Protein kinase A phosphorylates phosphorylase kinase.

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  • 比如说如果真正着迷蛋白激酶生物化学,不一定肿瘤学范围内研究激酶

    If one is really, for instance, captivated by the biochemistry of protein kinases, you don't necessarily have to work on kinases in oncogenesis.

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  • 蛋白激酶数量最多一类激酶作用修饰特定蛋白活性

    The largest group of kinases are protein kinases, which act on and modify the activity of specific proteins.

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  • 激酶缓冲液用来分析蛋白激酶活性

    Kinase Buffer can be used to assay protein kinase activity.

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  • 细胞外信号调节激酶丝裂原激活蛋白激酶家族重要成员

    The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.

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  • 丝裂原激活蛋白激酶细胞外信号调节激酶,具有神经元信号传导功能参与多种发育过程

    Mitogen activated protein (MAP) kinase, also known as extracellular signal regulated kinase, or ERK, functions in neuronal signal transduction and participates in diverse development processes.

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  • 非替尼为选择性EGFR一蛋白酪氨酸激酶抑制剂阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡

    Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.

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  • 结果表明:阿维链霉菌中存在61个组氨酸蛋白激酶其中30个组氨酸蛋白激酶包含了全部保守传递器结构

    The result showed that 61 histidine kinases were found in the genome and 30 histidine kinases contained total conserved transmitter domain.

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  • 研究表明保护效应蛋白激酶CPKC胞外信号调节激酶ERK)有关。

    It has been shown that its protective effect is related to protein kinase C (PKC) and extracellular signal-related kinase (ERK).

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  • 所有先天感染患儿临床UL145编码蛋白具有蛋白激酶C PKC磷酸化功能位点蛋白激酶(CK2)磷酸化功能位点。

    The UL145 protein of the clinical strains were conserved and comprised phosphorylation motif sites for protein kinase C(PKC) and casein kinase 2(CK2).

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  • 调节细胞能量状态蛋白激酶级联反应中,AMP激活蛋白激酶AMPK中枢组成部分

    AMP-activated protein kinase AMPK is a central component of a protein kinase cascade that plays a pivotal role in the regulation of intracellular energy status.

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  • 在此我们总结一些已经能用于心血管疾病蛋白激酶靶位以及一些鉴定与心血管疾病有关蛋白激酶假定治疗靶位的难点

    Here, we will review several kinds of protein kinases as potential targets for CVDs and some difficulty in identifying a protein kinase as a putative therapeutic target for CVDs.

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  • 蛋白激酶一种可以控制其他蛋白或是IKKE蛋白激酶看起来是作用调控小鼠代谢基因的。

    Protein kinases are enzymes that turn other proteins on or off. The IKKE protein kinase appears to target proteins which, in turn, control genes that regulate the mouse metabolism.

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  • 目的:研究低体温大鼠下丘脑蛋白激酶APKA)、蛋白激酶CPKC活性变化及桂枝汤的升温作用机理

    Objective:To observe the changes of the activity of protein kinase A(PKA) and C(PKC), and further investigate the mechanisms of anti-hypothermia action of Guizhi Tang.

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  • 腺苷酸激活蛋白激酶(AMPK)一种在酵母植物动物界高度保守的蛋白激酶,它能量平衡发挥关键性作用(1)。

    AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis (1).

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  • 下丘脑蛋白激酶C抑制剂卡马拉素OAG同时给药会抑制OAG活化蛋白激酶c能力降低葡萄糖生成

    Coadministration of hypothalamic PKC - inhibitor rottlerin with OAG prevented the ability of OAG to activate PKC - and lower glucose production.

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  • 结论AG110 9不仅酪氨酸蛋白激酶抑制剂而且一种十分有效蛋白激酶CK2的抑制剂。

    CONCLUSIONS AG1109 not only was an effective inhibitor of protein tyrosine kinases, but also was a novel potent inhibitor of protein kinase CK2.

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  • 发明涉及可用作蛋白激酶特别是JAK家族激酶抑制剂(i)化合物

    The present invention relates to compounds of formula (I) useful as inhibitors of protein kinases, particularly of JAK family kinases.

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  • 极光激酶AAIK种调节细胞周期的丝氨酸/苏氨酸蛋白激酶多种肿瘤细胞系中过表达(1-3)。

    Aurora A (AIK) is a cell cycle-regulated serine/threonine protein kinase that is overexpressed in many tumor cell lines (1-3).

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  • 主要观察指标:神经细丝磷酸化程度糖原合酶激酶3、细胞周期依赖性蛋白激酶5的活性

    MAIN OUTCOME MEASURES: The degree of NF phosphorylation and the activities of GSK-3 and CDK-5 were mainly observed.

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  • 主要观察指标:神经细丝磷酸化程度糖原合酶激酶3、细胞周期依赖性蛋白激酶5的活性

    MAIN OUTCOME MEASURES: The degree of NF phosphorylation and the activities of GSK-3 and CDK-5 were mainly observed.

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