结论本法准确可靠,操作简便,适用于缓释bcnu微球的体外药物释放动力学研究。
Conclusion This high performance liquid chromatography method is simple, sensitive and accurate. It is suitable for released kinetics study of controlled-release microspheres of BCNU loading in vitro.
对模型参数的最佳评价通过最小化模型模拟和实验测定间的药物释放动力学差别来获得。
Optimal estimates of the model parameters were obtained by minimizing the difference between model simulation and experimentally measured drug release kinetics.
本文应用荧光分光光度法研究了甲氨喋呤脂质体冻干粉针在几种输液中药物释放动力学。
This study deals with the release Dynamics of freezing dry injection of MTX Liposomes in infusion solution using fluorometric method.
经药物释放动力学的测试和灭菌效果试验表明,该材料具有较长的药物缓释周期和很好的抗菌活性。
The results of experiments of antibiotic release rates and antiseptic studies showed that the material has effective antibiotic activity.
用两种乳腺癌细胞株模型评价纳米粒介导的细胞药物释放动力学和机理及纳米粒包囊阿霉素的治疗效果。
Kinetics and mechanism of nanoparticle-mediated cellular drug delivery and therapeutic efficacy of nanoparticle-encapsulated doxorubicin were evaluated in two model breast cancer cell lines.
结果表明:甲氨喋呤脂质体的药物释放速率符合一级动力学方程。
The results showed that the drug release from MTX liposomes was in conformity with the first-order dynamic equation.
结果表明:研制缓释片的缓释效果良好,药物的释放符合一级动力学规律。
The results indicated that the sustained release tablets had an expected sustained release quality, and the drug release pattern was in accorded with the first order kinetics.
体外释放第一天呈突释效应,而后药物释放基本符合零级动力学过程。
The pattern of drug release for 30 days in vitro fitted to zero order release plot, with an initial burst effect at the first day.
结论建立了单室模型药物血管外给药零级释放和一级释放的药物动力学。
Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.
结论建立了单室模型药物血管外给药零级释放和一级释放的药物动力学。
Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.
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