• 可能其它药物相互作用特别是心血管一类药物,例如ace抑制受体阻滞剂保钾利尿剂。

    It can also interact with other medications, especially certain types of cardiovascular medications such as ACE inhibitors, receptor blockers and potassium-sparing diuretics.

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  • 但是近期报道已经表明两种药物之间有潜在危险相互作用由此质子泵抑制降低血小板药物实际效果

    But recent reports had suggested that there might be a potentially dangerous interaction between the two drug classes whereby PPIs reduce the actual effectiveness of antiplatelet agents.

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  • 药物相互作用风险会提高因为两种药物都会抑制CYP34 A代谢途径可能增加了依赖该代谢途径降解药物水平

    There's also an increased risk of drug-drug interactions, as both new agents inhibit the common CYP34A metabolic pathway, potentially increasing levels of other drugs metabolized that way.

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  • 目前确定候选药物出现此类相互作用可能性主要方法通过体外CYP450诱导抑制潜能的快速筛选。

    A rapid in vitro assessment of CYP450 induction and inhibition is a part of the current paradigms for identifying drug substances likely to be metabolized via such interactions.

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  • 而且CYP2D6多种药物竞争性抑制诱导药物联用时产生相互作用

    Meanwhile, many drugs can influence the activity of CYP2D6 by competitive inhibition or induction, which is easy to cause interaction in coadministration.

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  • 可能其他药物相互作用尤其是心血管药物例如ace抑制受体阻断剂保钾利尿药。

    It can also interact with other medications, especially certain types of cardiovascular medications such as ACE inhibitors, receptor blockers and potassium-sparing diuretics.

    youdao

  • 认识药物代谢基础,了解药酶常见底物诱导剂抑制合理选用同类药品避免有害药物代谢性相互作用的发生。

    The adverse drug interactions can be avoided by knowing the enzymology basis of drug metabolism, common substrates, inductors, inhibitors involved and using the same kind of drugs rationally.

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  • 结论CYP1A介导肉桂代谢转化主要系,肉桂酸抑制诱导CYP1A酶药物合用可能存在相互作用

    CONCLUSION CYP1A is the major enzyme in metabolism of cinnamic acid. The medicine, which have inducible and inhibitory effects on CYP1A, may have interaction with cinnamic acid.

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  • 结论CYP1A介导肉桂代谢转化主要系,肉桂酸抑制诱导CYP1A酶药物合用可能存在相互作用

    CONCLUSION CYP1A is the major enzyme in metabolism of cinnamic acid. The medicine, which have inducible and inhibitory effects on CYP1A, may have interaction with cinnamic acid.

    youdao

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