人体的循环系统里有一些有害的化学物质,血脑屏障是一道防御这些有害物质的天然屏障,但这道屏障同时也将治疗药物隔于脑外。
This barrier is a natural defence against potentially harmful chemicals floating around the body but has also stopped useful drugs reaching the brain as well.
方法应用透射电镜观察脑胶质瘤侵袭微生态系统中血瘤屏障的超微结构改变;
Methods The ultrastructure of blood tumor barrier in gliomas was observed by transmission electronic microscope.
糖蛋白抑制剂可促进药物通过血脑屏障,对提高脑内药物的浓度和中枢神经系统药物的生物利用度具有重要意义。
P-glycoprotein inhibitors can get drugs across the blood-brain barrier. It is of great importance to improve the blood concentration in brain and bioavailability of central nervous system drugs.
但血脑屏障的存在却使外源性基因难以进入脑内,是中枢神经系统转基因治疗的主要障碍。
But it is difficult for exogenous gene to enter brain because of the presence of the blood-brain barrier (BBB). This is the main obstacle for gene transfer therapy in central nervous system.
然而,血脑屏障也成为阻碍中枢神经系统治疗药物进入脑的主要障碍。
However, it also becomes the main obstacle of the entrance of the therapeutic drugs for central nerval system into the brain.
然而,血脑屏障也成为阻碍中枢神经系统治疗药物进入脑的主要障碍。
However, it also becomes the main obstacle of the entrance of the therapeutic drugs for central nerval system into the brain.
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