近二十年来，通过研究传统的单细胞耐药模型使我们对耐药机制有了一定的认识。
In the past twenty years, primary understanding of the mechanisms associated with drug resistance has been ascertained through investigating unicellular drug-resistant models.
此外，美国国际开发署还建立了一个多耐药模型项目(这个项目和肺结核、艾滋病服务是一体的)，在地区和当地宣传扩展肺结核专业知识。
Additionally, USAID created a model multi-drug resistant program, integrated TB and HIV services, and expanded TB expertise at zonal and local levels.
目的通过体外药效学模型探讨预测抑制细菌耐药突变的PK/PD参数折点。
Objective To determine the PK/PD parameters which is more dependent on the inhibition of resistant mutants using vitro pharmacodynamic model.
目的建立大鼠难治性癫痫模型并观察其特点及研究多药物耐药蛋白P-糖蛋白表达规律，探讨癫痫耐药机制。
ObjectiveTo establish and research the rat model of refractory epilepsy and investigate the rule of P-glycoprotein expression to make the mechanism of drug resistance clear.
目的建立卵巢癌A2 780细胞形成的多细胞团簇模型，探讨凋亡在卵巢癌细胞群集耐药中的作用。
Objective To explore an optimal model of multicellular aggregates of ovarian cancer cell line A2780 and investigate the possible mechanism of ovary cancer multicellular drug resistance.
第一部分是利用尽可能简化的理论模型描述大肠杆菌在耐药性上的表型分化现象。
The first part is to build the simplest model to describe the phenotype variation of bacterial drug tolerance.
目的：建立高效、稳定的人膀胱癌多药耐药性细胞模型。
Objective: To establish highly effective and stable multidrug resistance (MDR) bladder cancer cell line.
结论：基因转染法是建立人膀胱癌多药耐药细胞模型的理想方法。
Conclusion: The establishment of MDR cell lines by gene transfection is an ideal method.
结论：基因转染法是建立人膀胱癌多药耐药细胞模型的理想方法。
Conclusion: The establishment of MDR cell lines by gene transfection is an ideal method.
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