目的研究新生猪缺氧缺血脑损伤(HIBD)模型的制备。
Objective To develop an improved neonatal piglet model of hypoxic ischemic brain damage (HIBD).
研究谷胱甘肽对缺氧缺血脑损伤引起的神经细胞凋亡的作用。
To study the effects of glutathione on hypoxic ischemic brain damage in neonatal rats hippocampal.
目的探讨鹿石合剂对缺氧缺血脑损伤新生大鼠保护作用的机制。
Objective To explore the protective effect of Lushi mixture on hypoxic-ischemic brain damage neonatal rats.
缺血脑损伤大鼠皮层海马脑区的兴奋性氨基酸明显高于正常对照组。
The levels of exciting amino acids in hippocampi and cortex of ischemic brain injury rats were significant higher than those of controls.
目的研究外源性单唾液酸四己糖神经节苷脂（GM1）对新生鼠缺氧缺血脑损伤（HIBD）的保护作用。
AIM To study the protective effects of monosialotetrahexosylganglioside (GM1) after hypoxic ischemic brain damage (HIBD) in neonatal rats.
目的探讨N-乙酰半胱氨酸（NAC）对缺氧缺血脑损伤（HIBD）大鼠脑细胞间黏附分子-1及细胞凋亡的影响。
Objective To explore the effect of N-acetylcysteine (NAC) on intercellular adhesion molecule-1(ICAM-1) expression and apoptosis in neonatal rats brain after hypoxic and ischemic brain damage (HIBD).
在随访中，最初先兆头痛一个月发作一次或多次的女性有明显较高的小脑损伤风险，这些损伤好像是缺血性栓塞。
At the follow-up, women who originally reported having migrainewith aura once or more a month had a significantly higher riskof having lesions in the cerebellum that appeared to be ischemicinfarcts.
目的研究缺氧缺血新生猪凝血状态，以及部分凝血因子促凝活性的动态变化，探讨缺氧缺血性脑损伤（HIBD）时凝血功能变化。
Objective To investigate the changes of blood coagulation state and some prothrombin's function in newborn piglets at different time after hypoxic-ischemic brain damage (HIBD).
目的探讨超声诊断在新生儿缺氧缺血性脑病(HIE)各种脑损伤中的应用价值。
Objective To study the application of ultrasound diagnosis of various brain injury caused by hypoxic-ischemic encephalopathy (HIE).
结论STAT 3蛋白表达增强可能介导缺血性脑损伤的信号转导过程，其在脑缺血损伤神经元凋亡过程中起关键作用。
Conclusion the expressions of STAT3 increased might indicate the transmission course in ischemic nerve cell signal, and play a key role in neuron apoptosis of ischemic brain injury.
结论高压氧对缺血性脑损伤有显著治疗作用，提高脑红蛋白的表达水平可能是其治疗的机制之一。
Conclusion Hyperbaric oxygen treatment had an obvious effect on ischemic brain injury, and increasing the expression of Neuroglobin might be one of the possible mechanisms of the therapy.
目的探讨早期干预对缺氧缺血性脑损伤(HIBD)大鼠学习记忆能力及神经元凋亡的影响。
Objective to explore the influences of early interventions on learning, memory and neuron apoptosis in the brain of neonatal rats with hypoxic ischemic brain damage (HIBD).
结果迟发性颅内血肿、弥漫性脑肿胀、侧裂区脑挫裂伤、脑组织缺血、缺氧等是重型颅脑损伤术中急性脑膨出的主要原因。
Results The main cause of acute encephalocele were delayed intracranial hematomas, acute diffuse brain swelling, cerebral contusion and laceration in Sylvain tissue and ischemic anoxia.
目的观察缺氧缺血性脑损伤新生猪脑电生理的变化。
Objective To observe the electric physiologic changes in newborn piglets with HIBD.
通过亚低温对新生鼠缺氧缺血性脑损伤（HIBD）大脑皮质神经元一氧化氮合酶（NOS）及血糖水平影响的研究，探讨亚低温对缺氧缺血性脑损伤的保护作用机制。
Through investigating the effect of mild hypothermia on activity of nitric oxide synthase(NOS) in cortical neurons and glycemia levels of neonatal rats with hypoxic ischemic brain damage(HIBD).
目的研究新生动物缺氧缺血性脑损伤（HIBD）后脑细胞间粘附分子-1（ICAM- 1）在转录水平表达规律。
Objective To study the expression of ICAM 1 at gene transcription level in neonatal rats after hypoxic ischemic brain damage(HIBD).
苯妥英钠对缺血性脑损伤的神经保护作用与其能抑制自由基形成，减轻自由基介导的毒性，抗脂质过氧化反应以及扩张血管，增加局部脑血流量有关。
Phenytoin sodium may protect brain tissues from cerebral ischemic injury by inhibiting formation of free radical, anti-lipid peroxidation and improving regional cerebral blood flow.
结论：脑组织产生过量的NO和血浆NO的不足参与了缺血性脑损伤的过程。
Conclusions: Excessive NO produced in brain tissue and insufficient plasma NO participate the course of ischemic brain damage.
目的探索东莨菪碱对新生儿缺氧缺血性脑损伤（HIBD）的治疗作用。
Objective To evaluate treatment response of scopolamine for hypoxic-ischaemic brain damage(HIBD) in neonates.
结论：阿司匹林预处理对随后的缺血性脑损伤具有保护作用，其机制可能是抑制NOS活性，减少NO释放。
Conclusions: Aspirin preconditioning has neuroprotective effects for the subsequent ischemic cerebral injury. Its mechanism may be the inhibition of NOS activity and the reduction of NO release.
电针可以增加大鼠脑缺血区皮层ngf的分泌和表达时程，这可能是其保护缺血性脑损伤的机制之一。
Ea can increase the secretion and expression period of NGF in rats ischemic cortex, and this may be one of its protective mechanisms for ischemic cerebral damage.
结果纳入缺氧缺血性脑损伤患儿148例，全部进入结果分析，无脱落。
RESULTS: All the 148 cases of hypoxia-ischemia brain injury were involved in the result analysis.
缺血性脑损伤的病理生理机制包括兴奋性氨基酸的释放、梗死灶周围去极化、炎症反应及神经元凋亡等。
The pathophysiological mechanisms of ischemic cerebral injury involved in the release of excitatory amino acids, depolarization about the infarction, inflammatory reaction and neuron apoptosis.
目的探讨内源性一氧化碳（CO）在新生大鼠缺氧缺血性脑损伤（HIBD）中的作用机制及锡原卟啉的保护作用。
Objective To study the role of endogenous carbon monoxide(CO) in newborn rats with hypoxic-ischemic brain damage (HIBD) and the protective effect of Sn-protoporphyrin (SnPP).
目的：探讨阿司匹林预处理对缺血性脑损伤的保护机制及最佳剂量。
Objective: To study the neuroprotective mechanism of aspirin preconditioning in ischemic cerebral injury and its optimal dose.
结论：NOS抑制剂通过减轻缺血缺氧脑损伤时胎鼠脑神经细胞凋亡对其出生后的远期智能起保护作用。
Conclusion: NOS inhibitors play a obvious protective role in long-term intelligence of fetal rat after delivery through relieved neuron apoptosis during hypoxic ischemia encephalopathy.
目的：观察缺血性脑损伤对内源性神经干细胞增殖、迁移的影响。
AIM: To observe influences of ischemic brain injury on proliferation and transference of endogenous neural stem cells.
目的：探讨尼莫地平对磷脂酶a 2激活致急性缺血性脑损伤中的保护作用。设计：完全随机对照实验。
OBJECTIVE: To discuss the protective effects of nimodipine on acute ischemic brain injury caused by activation of phospholipase A2. DESIGN: a completely randomized controlled trial.
围产期窒息所致缺氧缺血性脑损伤(HIBD)是新生儿死亡和残疾的主要原因。
Hypoxia ischemic brain damage (HIBD), which resulted from neonatal asphyxia, is the main cause of death and disability in neonatal periods.
缺血性脑损伤的发生机制目前尚未明确，临床缺乏有效的治疗手段。
The mechanism of ischemic brain injury has not been elucidated thoroughly now, and there is no effective therapy in clinic.
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