• 提高预测精度:然而,序列中的顺序可以更好地描述序列结构类之间关系,尤其是抓…和。

    This is a flexible prediction method, based on which the knowledge of the query sequence can be utilized and the predictive accuracy be improved as a result.

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  • 针对问题,提出同时改进二级结构指定调整三种残基训练几率解决办法。

    Combining the advantage of the improvement of protein secondary structure assignment and proper modification for the probability of training will generate a better result.

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  • 氨酸残基对于蛋白质结构功能具有重要意义。

    Proline is very important to protein structure and function.

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  • 酪氨酸576酪氨酸577处于激酶结构激活这些残基突变减弱FAK催化活性6)。

    Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).

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  • 结果表明BSA芳香族残基受到干扰;二级结构也发生了变化

    The results showed the changes of the microenvironment of the aromatic amino acid residues and secondary structure of BSA.

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  • 该单克隆抗体通过重组蛋白免疫动物制备,该重组蛋白是人egfr1蛋白胞外结构附近残基

    Monoclonal antibody is produced by immunizing animals with a recombinant protein corresponding to the extracellular domain of human EGFR1 protein.

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  • 报道认为HIV抗药性RT一级结构的改变有关;

    There have been reported that the drug-resistance of HIV was correlated to the primary amino acid sequence of HIV-RT.

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  • 比较功能已知未知蛋白质结构同源性时,常常根据残基疏水性亲水性

    When the structural homology of proteins with known or unknown functions are compared, it is an usual way to base such comparisons on the hydrophobicity or hydrophilicity of the amino acid residues.

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  • 与此同时各种蛋白质一级结构多肽残基排列顺序不断被探测出来

    So much biological information has been accumulated. At the same time, many protein structures which are the peptide chain of amino acid sequences have also been detected.

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  • 一些蛋白质活性很重要进化过程中高度保守的,另有一些残基通过共进化维持蛋白质结构功能上的稳定。

    Some functionally important protein residues are highly conserved, while co-evolving residues are also able to preserve structure and function of proteins.

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  • 血管 生成 因子组成核糖核酸酶具有35%的同源性,它们有着极其相似的空间结构可以作为配体RI结合

    There is 35% homology between the amino acid residue of the Ang and RNase and their similar spatial structure can both combine with RI as ligand.

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  • 突变诊断复发获得的,导致截断保守残基组蛋白乙酰转移酶结构因或有害替代

    The mutations were either present at diagnosis or acquired at relapse, and resulted in truncated alleles or deleterious substitutions in conserved residues of the histone acetyltransferase domain.

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  • 论文主要单个残基水平上研究两个方面的问题,即肽链骨架构象二级结构倾向性

    This thesis contains the related studies mainly on two topics: their backboneconformations and their amino acid propensities.

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  • 论文主要单个残基水平上研究两个方面的问题,即肽链骨架构象二级结构倾向性

    This thesis contains the related studies mainly on two topics: their backboneconformations and their amino acid propensities.

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