提高预测精度:然而,残基在序列中的顺序可以更好地描述序列与结构类之间的关系,尤其是抓…和。
This is a flexible prediction method, based on which the knowledge of the query sequence can be utilized and the predictive accuracy be improved as a result.
针对问题,提出了同时改进二级结构指定和调整三种残基训练几率的解决办法。
Combining the advantage of the improvement of protein secondary structure assignment and proper modification for the probability of training will generate a better result.
脯氨酸残基对于蛋白质结构与功能具有重要意义。
Proline is very important to protein structure and function.
酪氨酸576和酪氨酸577处于激酶结构域的激活环,这些残基的突变减弱FAK的催化活性(6)。
Tyr576 and Tyr577 lie in the activation loop of the kinase domain, and mutation of these residues reduces FAK catalytic activity (6).
结果表明,BSA的芳香族氨基酸残基受到干扰;二级结构也发生了变化。
The results showed the changes of the microenvironment of the aromatic amino acid residues and secondary structure of BSA.
该单克隆抗体通过用重组蛋白免疫动物制备,该重组蛋白是人egfr1蛋白胞外结构域附近的残基。
Monoclonal antibody is produced by immunizing animals with a recombinant protein corresponding to the extracellular domain of human EGFR1 protein.
有报道认为HIV的抗药性与RT一级结构的氨基酸残基的改变有关;
There have been reported that the drug-resistance of HIV was correlated to the primary amino acid sequence of HIV-RT.
在比较功能已知或未知蛋白质的结构同源性时,常常是根据氨基酸残基的疏水性或亲水性。
When the structural homology of proteins with known or unknown functions are compared, it is an usual way to base such comparisons on the hydrophobicity or hydrophilicity of the amino acid residues.
与此同时各种蛋白质一级结构,即多肽链的氨基酸残基的排列顺序也在不断被探测出来。
So much biological information has been accumulated. At the same time, many protein structures which are the peptide chain of amino acid sequences have also been detected.
一些对蛋白质活性很重要的残基在进化过程中是高度保守的,另有一些残基通过共进化来维持蛋白质结构和功能上的稳定。
Some functionally important protein residues are highly conserved, while co-evolving residues are also able to preserve structure and function of proteins.
血管 生成 因子的氨基酸残基组成与核糖核酸酶具有35%的同源性,它们有着极其相似的空间结构都可以作为配体与RI结合。
There is 35% homology between the amino acid residue of the Ang and RNase and their similar spatial structure can both combine with RI as ligand.
的突变在诊断或复发时获得的,和导致截断保守的氨基酸残基的组蛋白乙酰转移酶结构域的基因或有害的替代。
The mutations were either present at diagnosis or acquired at relapse, and resulted in truncated alleles or deleterious substitutions in conserved residues of the histone acetyltransferase domain.
本论文主要在单个残基水平上研究两个方面的问题,即肽链骨架构象与氨基酸对二级结构的倾向性。
This thesis contains the related studies mainly on two topics: their backboneconformations and their amino acid propensities.
本论文主要在单个残基水平上研究两个方面的问题,即肽链骨架构象与氨基酸对二级结构的倾向性。
This thesis contains the related studies mainly on two topics: their backboneconformations and their amino acid propensities.
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