目的研究猪主动脉瓣膜去细胞基质的体外降解过程。
AIM To study the degradation behavior of acellular porcine aorta valve in vitro.
背景:硫酸软骨素是细胞基质的重要成分,可促进肿瘤细胞的增殖,抑制其转移。
BACKGROUND: Chondroitin sulfate is the important component of cell matrix, it can accelerate the proliferation of tumor cells and restrain its transfer.
丝类支架可以被用作组织工程学领域的细胞基质,它能提供细胞生长所需的立体环境。
Silk scaffolds are used as a cell substrate in tissue engineering, providing a three-dimensional environment in which cells can grow.
罪魁祸首就是胸腺基质淋巴生成素(简称TSLP),这是一种由受损的皮肤分泌的信号分子,受损的皮肤引起身体强烈的免疫反应以便对抗入侵细胞。
The culprit is thymic stromal lymphopoietin (TSLP), a signalling molecule secreted by damaged skin cells which elicits a strong immune response from the body to fight off invaders.
据美国《大众科学》杂志1月14日报道,美国研究人员日前利聚乙二醇在无毒塑料基质上成功培育出毛细血管,并且可以控制细胞在塑料凝胶中的生长方向。
Researchers from Rice University and Baylor College of Medicine grew a system of and capillaries on a nontoxic plastic matrix. They were able to control where cells grew in their plastic gel.
为了找到答案,他和他的同事在不同硬度的基质上培育胚胎心脏细胞。
To find out, he and his colleagues grew embryonic heart cells on matrixes of differing stiffness.
迪斯凯尔认为,不停软化那些硬化基质的工作耗尽了细胞的精力。
The constant work of trying to flex the stiffer matrix wears the cells out, Discher thinks.
接着,他们用另外的工程删除在肺部接收胸腺基质淋巴细胞生成素的感受器分子的基因。
Then they used additional engineering to delete the gene for the receptor molecule which picks up TSLP in the lungs.
血细胞以外的大多数细胞都生活在纤维细胞外基质里。
Most cells other than blood cells live within a fibrous extracellular matrix.
为了得到用于组织工程的单个细胞,研究者们首先必须将组织分离打散,即用酶消化原本组织中连接细胞的细胞外基质。
To obtain single cells for tissue engineering, researchers have to first break tissue apart, using enzymes that digest the extracellular material that normally holds cells together.
细胞膜内一种称为整合素的蛋白质将每个细胞与基质相连,同时细胞内部的蛋白架构不断牵引着这些整合素,创建出一个拉紧的、协调的整体。
Each cell is linked to this matrix by proteins in its membrane called integrins, and the cell's internal protein skeleton is constantly tugging on these integrins to create a taut, tuned whole.
科学家必须解决如何抑制某些部位的运动,比如恶化的肿瘤周围的细胞外基质。
Instead, scientists will have to figure out how to block movement in select locations, like in the extra-cellular matrix around growing tumors.
在长时间里,可能发明出一种药物,就是能抑制胸腺基质淋巴细胞生成素的产物或者干扰肺部里的胸腺基质淋巴细胞生成素感受器分子。
In the longer term, it might be possible to devise drugs that inhibit the production of TSLP or interfere with TSLP-receptor molecules in the lungs.
第三,他们设计让老鼠在它们没有其他皮肤问题的情况下,在它们的皮肤里产生高水平的胸腺基质淋巴细胞生成素。
Thirdly, they engineered mice to produce high levels of TSLP in their skin in the absence of other skin problems.
移动的细胞采用点对点附着体系,就像小钩一样捕捉构成细胞外基质的物质。
Anyway, cells on the go use a point-to-point adhesion system, which functions like tiny hooks, to grab the materials that make up the extracellular matrix.
还有证据表明,各种基质细胞在正常和病理的血管生成在一个组织或上下文特定的方式参与。
There is also evidence that various stromal cell types participate in normal and pathological angiogenesis in a tissue - or context-specific fashion.
细胞外基质是一种胶状物质,如果你愿意,会将我们身体的所有细胞聚合在一起。
The extracellular matrix is the glue, if you will, that holds all of the cells in our body together.
研究表明,移植物中的胶原蛋白部分与材料基质中的成纤维细胞和成骨细胞的结合密切相关。
The portion of collagen protein incorporated in the graft is thought to be responsible for binding fibroblasts and osteoblasts in the material matrix.
科学家将一种取自于斑马鱼心脏的“细胞外基质”注入严重受损的老鼠心脏中。
Scientists injected an "extracellular matrix, " or ECM, from the heart of a zebrafish into a severely damaged mouse heart.
四种软骨各自有不同的细胞和细胞外基质特征。
These four kinds of cartilages were characteristic of respectively different chondrocyte and extracellular matrix.
这些肿瘤细胞产生了一整系列的蛋白酶,能降解包围它们的细胞外基质蛋白,这也是部分的基底膜。
The tumor cells produce a whole range of proteases that degrade the proteins of the extracellular matrix that hems them in, part of which is the basement membrane.
失巢凋亡是一种当细胞与其周围的基质和邻近细胞分离后而被启动死亡的过程。
Anoikis is the process by which cells are triggered to die when separated from their surrounding matrix and neighboring cells.
目的:探讨胎儿骨髓基质细胞与外源性细胞因子的协同造血支持作用。
Objective: to elucidate the role of bone marrow stromal cells in cooperation with exogenous cytokines in hematopoiesis.
提取的骨髓基质细胞呈贴壁生长,诱导后可向成骨细胞分化,细胞呈成骨细胞形态为梭形和多角形。
BMSC grew by static adherence, differentiated to osteoblasts and had strong capacity of proliferation, the shape of cells was fusiform or polygon, like osteoblasts.
它们的高度存在意味着基质可能在癌细胞到达新的目的地后诱导其向上皮性转变,所以它们能够使一个新的癌灶稳定生长。
Their heavy presence implies that the stroma may have induced the cancer cells to revert to epithelial when they reached a new destination, so they could stabilize to populate a new tumor site.
在生物学中,细胞外基质是细胞产生和释放的一种物质,它能够向周围细胞提供结构和生化支持。
In biology, an extracellular matrix is a substance produced and released by cells that gives structural and biochemical support to surrounding cells.
其主要的功能是产生II I型胶原,弹性蛋白和肺泡隔细胞外基质中的蛋白多糖。
Their principle function is production of type III collagen, elastin, and proteoglycans of the extracellular matrix of the alveolar septa.
其主要的功能是产生II I型胶原,弹性蛋白和肺泡隔细胞外基质中的蛋白多糖。
Their principle function is production of type III collagen, elastin, and proteoglycans of the extracellular matrix of the alveolar septa.
应用推荐