免疫组化法观察细胞周期调控蛋白的表达变化。
The expression of protein related cell cycle was observed by immunohistochemical.
背景：细胞周期调控蛋白水平及其相互关系是良恶性细胞增殖的主要区别标准。
BACKGROUND: the different level of proteins regulating cell cycle and their correlation is the main criteria to differentiate the benign and malignant cellular proliferation.
生物学中的许多现象如细胞凋亡、细胞周期调控、信号转导和癌变等均受蛋白质间相互作用的调控。
Many phenomena in biology, such as apoptosis, cell cycle control, signal transduction and canceration and etc, are all regulated by the interaction of proteins.
热休克蛋白可能有助于细胞周期调控通过与原癌基因的产品或抑癌基因的产品。
Heat Shock Proteins may contribute to cell cycle regulation by interacting with proto-oncogene products or tumor suppressor gene products.
衰老细胞呈现变革中的蛋白的表达调控细胞周期。
Senescent cells exhibit changes in the expression of proteins that regulate the cell cycle.
细胞周期调控机制的核心是一组蛋白激酶。
The core of cell cycle regulation and control mechanism are relative to a group of protein kinase.
本文将从细胞周期的调控，细胞周期蛋白d1的发病机制及其与口腔扁平苔藓癌变的联系简要综述。
We reviewed researches on the regulations of cell cycle, the pathogenesis of CyclinD1, and their association with the cancerization of OLP.
泛素- 蛋白酶体通路介导细胞蛋白质的降解，在细胞周期、基因转录及表达、 抗原提呈和炎症演进等方面发挥调控作用。
Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development.
在植物中a型和B型细胞周期蛋白依赖性激酶直接参与调控细胞周期。
In plants, a - and B-type CDKs are directly involved in cell cycle regulation.
结论：DCN可能为一种负性调控蛋白，可通过调节细胞周期，抑制肝癌细胞的增殖，促进其凋亡。
CONCLUSION: DCN may be a negative regulatory protein inhibiting hepatoma carcinoma cell proliferation through inhibiting cell cycle and inducing apoptosis of cell in vitro.
他们发现，由一个分子对另外一个EGFR激酶结构域的不对称激活类似于涉及调控细胞生长的细胞周期蛋白激活细胞周期蛋白依赖型激酶的方式。
They found that the asymmetric activation of one EGFR kinase domain by another is analogous to the activation of cyclin-dependent kinase (CDK) by cyclin, which are involved in regulating cell growth.
组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控，影响特定基因的表达，改变细胞周期的进程。
HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.
组蛋白脱乙酰基酶与组蛋白脱乙酰基酶抑制剂通过对组蛋白乙酰化水平的调控，影响特定基因的表达，改变细胞周期的进程。
HDAC and histone deacetylase inhibitors (HDI) can affect expression of some specific genes and induce cell differentiation growth arrest and apoptosis through regulating histone acetylation level.
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