现对尼古丁调控细胞凋亡相关的各种信号通路及其分子机制进行综述。
This paper mainly reviews the signal pathways and molecular mechanisms of nicotine in apoptotic regulation.
进一步阐明心肌细胞凋亡的信号通路，将为CHF的预防和治疗提供新的途径。
Further elucidation of the signal pathway leading to cardiomyocyte apoptosis may open new routes to prevention and treatment of CHF.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂，能阻断酪氨酸蛋白激酶信号传导通路，从而促进肿瘤细胞凋亡。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
MAPK信号转导通路是一条关键的调节细胞增生和凋亡的通路。
MAPK signaling transduction is a key pathway of cellular proliferation and apoptosis regulation.
颗粒细胞凋亡相关蛋白通过参与凋亡通路及凋亡信号转导调节凋亡。
Apoptosis-associated proteins regulate apoptosis through taking part in the apoptosis pathway and the signal transduction in apoptosis.
活性氧通过信号通路介导心肌细胞肥大和凋亡；通过灭活一氧化氮等机制导致内皮功能紊乱。
Reactive oxygen species can mediate signalling pathways in cardiac hypertrophy and cardiomyocyte apoptosis, and lead to endothelial dysfunction by inactivating nitrogen monoxide.
GSK3底物众多，其功能与细胞的存活与凋亡，结构与能动性以及细胞内众多信号传导通路密切相关。
GSK3 regulates many functions including cell survival and apoptosis, structure and motility, intracellular signaling pathways and so on.
近年来在凋亡机制的研究中发现内质网应激反应介导的细胞凋亡是一条新的细胞凋亡信号传导通路。
In recent years, the study found that the apoptosis mechanism of endoplasmic reticulum stress-mediated apoptosis is a new signaling pathway of apoptosis.
药物的作用机制尚不清楚，可能的作用包括血管收缩、调节信号传导通路和促进内皮细胞凋亡。
The drugs' mechanism of action remains uncertain, but plausible theories include vasoconstriction, modulation of pro-survival signal transduction pathways, and endothelial cell apoptosis.
目的：探讨e2 F1蛋白信号的转导通路对胆管癌细胞凋亡的影响中的作用。
Objective: to study the action of E2F1 protein signal transmission pathway to influence the apoptosis of cholangiocarcinoma QBC939 cells.
目的：探讨e2 F1蛋白信号的转导通路对胆管癌细胞凋亡的影响中的作用。
Objective: to study the action of E2F1 protein signal transmission pathway to influence the apoptosis of cholangiocarcinoma QBC939 cells.
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