本发明属于植物基因工程技术领域，具体涉及一种水稻组蛋白去甲基化酶基因及其编码蛋白与应用。
The invention belongs to the technical field of plant gene engineering, and more particularly relates to a paddy rice histone demethyl methylase gene, coded protein and the application thereof.
组蛋白赖氨酸去甲基化酶有可能成为一个新的抗肿瘤治疗靶标。
Therefore, histone lysine demethylases may serve as a new target for anti-cancer therapy.
随着组蛋白赖氨酸去甲基化酶的发现，证实组蛋白赖氨酸甲基化是一个可以逆转的组蛋白表遗传修饰。
The discovery of the histone lysine demethylases has strongly demonstrated that histone lysine methylation is a reversible epigenetic modification.
靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。
Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.
SDS - PAGE、圆二色谱和MALDI - TOF质谱分析结果表明，成功获得纯度较高的重组蛋白，且具有去甲基化的活性。
Results of SDS-PAGE, CD and MALDI-TOF showed that the recombinant protein was obtained successfully with high purity and possessed demethylation activity.
SDS - PAGE、圆二色谱和MALDI - TOF质谱分析结果表明，成功获得纯度较高的重组蛋白，且具有去甲基化的活性。
Results of SDS-PAGE, CD and MALDI-TOF showed that the recombinant protein was obtained successfully with high purity and possessed demethylation activity.
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