目的从群体角度探讨胰岛素抵抗与胰岛素受体基因多态性的关系。
Objective To understand the role of insulin-receptor gene in the development of insulin resistance on a population-based study in China.
黑素皮质素受体基因变异也可能在深色头发的人群中发生，但几率较小。
The mutation in the MC1R gene also occurs in brunets, although it's less common.
综述了各个黑素皮质素受体基因的结构、表达调控及多态性等研究进展。
The recent progress in the structure, expression control and polymorphism of these melanocortin receptor genes was summarized in the paper.
目的探讨SW872前脂肪细胞分化过程中脂联素受体基因表达的变化。
Objective to explore genes expression of adiponectin receptors during differentiation of SW872 preadipocytes.
结论：瘦素受体基因外显子4中519位点变异不是肥胖症的遗传因素。
CONCLUSION: Variation of exon 4 in LEPR gene at site 519 is not a genetic factor of obesity.
目的探讨胰岛素受体基因外显子17与多囊卵巢综合征（PCOS）发病的关系。
Objective To investigate insulin receptor (INSR) genotype exon 17 frequencies in women with polycystic ovary syndrome(PCOS) and to elucidate its role in the pathogenesis of PCOS.
换句话说，是血清素受体基因的某个特定遗传突变，而不是雇主的激励，使得人们对自己的工作更满意。
In other words, it may be a particular genetic mutation of a serotonin-receptor gene, and not the employer's incentives, say, that is making people happier with their work.
目的：观察胰岛素受体基因第17外显子基因多态性与中国人脑梗死和原发性高血压的相关性。
AIM: to observe the correlation of the 17 exon gene polymorphism of insulin receptor gene and the Chinese cerebral infarction and primary hypertension.
目的：观察胰岛素受体基因第17外显子基因多态性与中国人短暂性脑缺血发作和原发性高血压的关联。
AIM: to observe the association of insulin receptor gene exon 17 polymorphism with the transient ischemia attack and essential hypertension in Chinese.
在褐色头发、黑头发和金发的人群中，黑素皮质素受体基因(melanocortin - 1receptor)能分泌黑色素。
In people with brown, black and blond hair, the gene, for the melanocortin-1 receptor, produces melanin.
结论单纯型肥胖儿童瘦素受体基因第20外显子存在基因多态性的变化，且这种变化明显影响肥胖儿童的脂质代谢及体脂分布。
Conclusion There is polymorphism at 20 exon LEPR gene in children with obesity, which may affect the lipid metabolism and the fat distribution.
这个变异称为IVS5-13insC，造成HMGA1蛋白的功能损伤，HMGA1蛋白是调节胰岛素受体基因（INSR）表达的辅助因子。
The variant, designated IVS5-13insC, impairs function of the HMGA1 protein, a cofactor for gene activation that regulates insulin-receptor gene (INSR) expression.
方法采用聚合酶链式反应-单链构象多态性方法检测46例高血压患者和39例正常血压对照者的胰岛素受体基因第17、18外显子的多态性。
Methods The polymorphism if exon 17 and 18 of insulin gene were detected in 46 hypertension patients and 39 normal controls using PCR and single strand conformation polymorphism.
方法：对原发性高血压伴胰岛素抵抗患者胰岛素受体基因酪氨酸激酶域外显子17、18基因突变进行检测，并对突变的外显子进行核苷酸序列分析。
Methods: Using PCR SSCP, we detected the mutation of INSR tyrosine kinase domain exon 17 and exon 18 in 33 primary hypertension patients and 28 normal persons.
他从先前的研究中得知，某些种类的精神抑郁症，像是季节性情绪紊乱(或者冬季抑郁症)，与一个叫HTR2A的血清素受体基因的某个特定变异体有关。
He knew from previous research that some forms of melancholia, such as seasonal affective disorder (or winter blues), have been linked to particular versions of a serotonin-receptor gene called HTR2A.
选择89例非胰岛素依赖性糖尿病(NIDDM)患者，扩增胰岛素受体基因的外显子17 -21,sscp电泳，银染色后，对突变样品进行序列分析。
NIDDM were collected. Exon 17 ~ 21 of insulin receptor gene were amplified by PCR and screened by SSCP electrophoresis. After silver staining, the mutation samples were sequencing.
首先，他引入了一种能够导致肌生成抑制素的受体受到抑制的基因，使肌肉细胞的细胞膜表面的分子收到停止生长的信息。
First, he has introduced a gene that turns out a stunted version of the myostatin receptor, the molecule that sits in the surface membrane of muscle cells and receives the message to stop growing.
该基因影响血管紧缩素受体系统，该系统在雄性橙腹田鼠的社会化一夫一妻行为中起关键作用。
This gene affects the angiotensin receptor system that plays a critical role in social monogamy for male prairie voles.
这两种基因产生与上述受体结合的大量蛋白质，压制和削弱有功能肌肉生长抑制素分子的作用。
These churn out proteins which bind to the receptors, swamping and diluting the effect of functional myostatin molecules.
目的研究中国湖北汉族人群内皮素受体- B (EDNRB)基因的多态性与散发性先天性巨结肠症发病的关系。
Objective To analyze the relationship between polymorphisms of EDNRB gene and Hubei provincial patients of Han ethnicity with sporadic Hirschsprung disease (sHD).
目的探讨维生素D受体（VDR）基因多态性与中国人自身免疫性肝炎（AIH）和原发性胆汁性肝硬化（PBC）发病的相关性。
Objective To study the association between the polymorphisms of vitamin D receptor (VDR) gene and autoimmune liver diseases and (AIH) and primary biliary cirrhosis (PBC) in Chinese.
目的探讨胰腺癌细胞（PC-3）胰岛素样生长因子-1受体（IGF- 1R）基因的定量表达，及其与细胞凋亡、成瘤性的关系。
Objective To explore Insulin like growth factor 1 receptor(IGF 1R)gene quantitative expression in human pancreatic cancer cells(PC 3) and the relationship of IGF 1R with apoptosis?tumorigenicity.
目的研究胰岛素样生长因子i受体(IGFIR)基因表达对脐血t淋巴细胞功能的影响及其临床意义。
Objective to study the role of insulin like growth factor type I receptors (IGF IR) in the modulation of cord blood t lymphocyte functions and its clinical significance.
方法：研究160例乳腺癌患者和140名对照者的维生素D受体基因在3'端的多态性。
METHODS: A total of 160 cases and 140 control subjects were studied for the polymorphisms at 3' end of the VDR gene.
目的观察瘦素对大鼠肝细胞瘦素受体蛋白、基因表达及酪氨酸磷酸化的影响。
Objective to investigate effects of leptin on gene and protein expression and tyrosine phosphorylation of leptin receptor in rat hepatocytes.
目的：研究不同膳食组成对小鼠肌肉胰岛素受体及其相关底物基因表达的影响。
Objective: to investigate the influence of nutrient on the expression of insulin receptor and its related substrate genes in the muscle of mice.
瘦素是肥胖基因的表达产物，通过与其受体结合发挥其生物学作用。
The leptin is a expression product of the obesity gene. Biological effect of leptin-has appeared by combination with its receptor just.
目的观察纳洛酮对内毒素刺激的大鼠离体支气管平滑肌细胞内皮素1和内皮素A受体基因表达的影响。
Objective To investigate the effect of naloxone on the expression of ET 1 and ET AR mRNA in cultured rat bronchial smooth muscle cells stimulated by LPS.
目的探讨血瘦素水平和瘦素受体（LR）基因多态性对胰岛素敏感性影响及与缺血性脑血管病发病的关联。
Objective To study the effects of plasma leptin level and leptin receptor(LR) gene polymorphism on the insulin sensitivity and their relation to ischemic stroke.
目的探讨血瘦素水平和瘦素受体（LR）基因多态性对胰岛素敏感性影响及与缺血性脑血管病发病的关联。
Objective To study the effects of plasma leptin level and leptin receptor(LR) gene polymorphism on the insulin sensitivity and their relation to ischemic stroke.
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