目的建立一种快速、体外筛选晚期糖基化终产物(age)交联结构裂解剂的方法。
AIM To establish a rapid method for screening advanced glycation end product (AGE) cross links breaker in vitro.
方法：应用竞争性el IS A法检测慢性肾功能衰竭患者(非血液透析组及血液透析组)血清晚期糖基化终产物水平。
Methods The serum advanced glycosylation end products in patients with chronic renal failure (hemodialysis group and non-hemodialysis group) were measured with competitive ELISA.
一旦进入血液中，糖分就会与蛋白质融合产生糖基化终产物(缩写为ages)。AGEs导致胶原蛋白挥发变硬产生皱纹。
Once in the bloodstream, sugar bonds with protein and creates advanced glycation end products (aptly abbreviated AGEs), which cause collagen to become inflamed and stiff, leading to wrinkles.
目的研究晚期糖基化终产物（AGE）修饰蛋白对人内皮细胞分泌单核细胞趋化蛋白1（MCP 1）的影响及其作用的信号传导途径。
Objective To investigate the effects of advanced glycation end products (AGE) on secretion of monocyte chemoattractant protein-1(MCP-1) by human endothelial cells and its signal transduction pathway.
总之，食物中的晚期糖基化终产物含量越高，血液中的晚期糖基化终产物水平就越高，C反应蛋白和其他一些炎症标记分子的水平就越高。
Overall, the higher the participants' consumption of foods rich in AGEs, the higher their blood levels of AGEs and the higher their levels of C-reactive protein and other biomarkers of inflammation.
这项研究包括172名健康者，年龄在18到45岁之间和60到80岁之间，研究发现在受试者中，64岁及以上的人晚期糖基化终产物的含量比45岁以及以下的人高35%。
The study of 172 healthy men and women, ages 18-45 and ages 60-80, found that AGE levels were 35 percent higher in participants age 64 and older than in those younger than age 45.
这项研究包括172名健康者，年龄在18到45岁之间和60到80岁之间，研究发现在受试者中，64岁及以上的人晚期糖基化终产物的含量比45岁以及以下的人高35%。
The study of 172 healthy men and women, ages 18-45 and ages 60-80, found that AGE levels were 35 percent higher in participants age 64 and older than in those younger than age 45.
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