目的探讨丙烯腈(acn)对睾丸精原细胞dna的损伤作用及经肝微粒体酶活化前后该损伤程度的差异。
Objective to explore acrylonitrile (ACN) induced DNA damage on Newt spermatogonia, and to compare the difference in DNA damages before and after microsomal enzyme activation.
不完善的静脉网络产生于15- 25岁之间,虽然没有常见的严重症状且不影响正常生活,但是有时可使睾丸疼痛和损伤。
The networks of faulty veins usually develop between the ages of 15 and 25. They are often harmless and lead to no serious symptoms, but can at times cause pain and damage the testis.
应用单细胞凝胶电泳技术,研究了烷基酚类化合物对离体小鼠睾丸细胞DNA的损伤作用。
The single cell gel electrophoresis technique (SCGE) was used to detecte the DNA damage of spermary cell in mice, which were induced by 9 tested environmental endocrine disrupting chemicals.
ACN对大鼠睾丸中ABP和抑制素基因表达水平有影响,提示丙烯腈对睾丸中支持细胞可能有损伤作用。
The results indicate that ACN could induce changes in the levels of ABP and inhibin gene expression in testes of male SD rats, that may damage Sertoli cells in testes.
结论1%焦亚硫酸钠喂食后,引起小鼠睾丸组织细胞损伤,提示1%焦亚硫酸钠对小鼠有生殖毒性作用。
Conclusion After a feeding of 1% sodium metabisulfite solution, testis tissue showed hydropic degeneration, that is, toxic effect on mice reproduction can be caused by overdose sodium metabisulfite.
应用小鼠骨髓微核试验及小鼠睾丸染色体畸变试验,测试蜂胶对诱变剂诱发的染色体损伤的保护作用。
Micronucleus test of bone marrow cells and chromosome aberration test were performed in mice to assess the antagonistic effect of propolis to mutation induced by mutagens.
实验研究表明ESW可造成睾丸形态结构破损、生精功能下降,但此损伤是暂时的、可逆的;
ESW can cause the damage to the structure and function of testis that are temporary and reversible.
目的:研究叶下珠(PU)提取物对盐酸氮芥(HN2)损伤睾丸组织N -钙粘蛋白表达的保护作用。
Objective: To explore the protective effect of the Phyllanthus Urinaria (PU) extract on the N-cadherin expression in the testicular tissues disrupted by nitrogen mustard (HN2) in vivo.
采用冷胰酶消化法分离培养大鼠睾丸支持细胞,采用单细胞凝胶电泳法检测亚硝酸钠对大鼠睾丸支持细胞dna的损伤作用。
Method: The effects of sodium fluoride on DNA damage and repair in isolated male mice testicular cells were observed with single cell gel electrophoresis test (Comet assay).
采用冷胰酶消化法分离培养大鼠睾丸支持细胞,采用单细胞凝胶电泳法检测亚硝酸钠对大鼠睾丸支持细胞dna的损伤作用。
Method: The effects of sodium fluoride on DNA damage and repair in isolated male mice testicular cells were observed with single cell gel electrophoresis test (Comet assay).
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