目的:用SELDI蛋白质芯片技术检测HBV感染携带者与肝细胞癌(HCC)患者血清蛋白质谱的差异性表达,以发现HCC的早期诊断标志物。
Object Using SELDI protein chip technology to detect the different serum protein spectrum of HBV infected carriers and HCC patient , and to explore serum markers for diagnosis of HCC.
结论CA125不只是卵巢癌的指标,也是一种广谱肿瘤标志物,并且肝硬化等良性疾病也有较高的阳性率,可作为健康体检中筛选异常人群的指标。
Conclusion: CA125 is not only a marker for ovarian cancer, but a broad-spectrum tumor marker. There are higher positive rates of CA125 in some benign diseases including hepatocirrhosis.
目的比较不同转移潜能人肝癌细胞系的基因表达谱,寻找与癌转移相关的基因表达改变。
Objective to compare gene expression profile of human hepatocellular carcinoma (HCC) cell lines with different metastatic potentials, so as to screen for metastasis-related genes.
目的:建立人卵巢癌紫杉醇耐药细胞株,探讨其基因表达谱差异与紫杉醇耐药之间相关性。
Objective: To establish paclitaxel (taxol) -resistant human ovarian carcinoma cell line and investigate the relation - ship between gene differential expression and taxol resistance.
结果显示,脐血与食管癌患者血清样的微量元素谱有显著差异,为脐带血的基础研究和临床应用提供了新的根据。
The results show that the TE-spectrum was different obviously between the serum of cord blood and EC-patients, which supplied a new basis for basic research and clinic application of cord blood.
目的:检测贲门癌高发区人群慢性萎缩性贲门炎(CAG)患者血清蛋白质质谱变化。
Aim: To determine the changes of serum proteomic image of chronic atrophic gastric-carditis subjects (CAG) from high risk population for gastric cardia adenocarcinoma (GCA).
方法首先从全基因组表达谱中筛选到鼻咽癌候选癌基因CSE1L。
METHODS CSE1L gene was sifted from the whole genome expression profiling from homogenous NPC and non-NPC biopsy tissue samples.
抗癌活性肽;胆囊癌;细胞系;基因芯片;基因表达谱。
Anti-cancer bioactive peptide (ACBP); Gallbladder carcinoma; Cell line; Gene chip; Gene expression pattern.
目的应用基因微矩阵技术分析原发性食管癌基因表达谱,筛选与食管癌进展相关基因。
OBJECTIVE: This study was to investigate the differentially expressed genes between primary esophageal squamous cell carcinoma and normal esophageal mucosa using cDNA microarray.
目的分析食管鳞状细胞癌(ESCC)患者血清蛋白表达谱的改变;
Objective To analyze the alterations of serum protein in ESCC, compare alterations of serum protein with and without LM.
应用微矩阵表达谱基因芯片筛选食管癌新的相关基因。
Study of the changes of gene expression during the process of liver fibrosis by cDNA microarray;
应用微矩阵表达谱基因芯片筛选食管癌新的相关基因。
Study of the changes of gene expression during the process of liver fibrosis by cDNA microarray;
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