称之为肿瘤抑制基因的突变可以引起生长失去控制,从而可能导致癌症。
Mutations in so-called tumor suppressor genes can result in loss of growth control, which in turn may result in cancer.
他们发现,史蒂芬.奎克罹患“心肌梗塞,第二类糖尿病和其他几种癌症的基因发病风险在上升”,最后使得奎克决定服用预防这类疾病的抑制素药物。
They found he had an “increased genetic risk for myocardial infarction, type 2 diabetes, and some cancers, ” and Quake decided to take a prophylactic statin as a result.
通过去甲基化或重新激活DNA甲基化所沉默的肿瘤抑制基因,它们可能为干细胞重新编程和癌症研究提供非常重要的信息。
It could also inform cancer research, as it could give scientists the opportunity to reactivate tumor suppressor genes that had been silenced by DNA methylation.
当Thompson开始研究这个基因时,他发现RTVP - 1基因是肿瘤抑制基因p53的靶基因,p 53是前列腺癌及其他癌症细胞活性的最主要控制者。
As Thompson began to study the gene, he found that it was a target for a tumor suppressor gene called p53, which is a major controller of cell activity in prostate and other cancers.
多数常见癌症中,肿瘤抑制基因FHIT的表达因受遗传或表观遗传因素的作用而受到抑制。
The tumor suppressor gene FHIT is inactivated by genetic and epigenetic changes in the majority of common human cancers.
研究人员瞄准进一步改善NMD -CGH基因芯片技术,并将之应用于发现前列腺癌以及其它癌症的尚未被发现的肿瘤抑制基因。
The researches aim to develop the NMD-CGH microarray method further and apply it for new tumour-suppressor gene discovery approaches in prostate cancer and other cancer types.
研究人员瞄准进一步改善NMD -CGH基因芯片技术,并将之应用于发现前列腺癌以及其它癌症的尚未被发现的肿瘤抑制基因。
The researches aim to develop the NMD-CGH microarray method further and apply it for new tumour-suppressor gene discovery approaches in prostate cancer and other cancer types.
应用推荐