肿瘤是各种原因导致多基因突变累积和相互作用形成的基因网络调控的结果,通过干预致瘤因子可能达到治疗肿瘤或改变肿瘤特性的目的。
Tumors are the results of accumulation of multiple gene mutations and their interactions. So by the intervention on tumorigenic factors, we may cure tumors or change their properties.
目前治疗胶质母细胞瘤的疗法直接采用抑制另一种细胞受体,即上皮生长因子受体(EGFR)。
Current therapies to treat glioblastomas are directed toward blocking the activity of another cellular receptor called epithelial growth factor receptor (EGFR).
黑色素瘤确定的危险因子之一是紫外线,所以暴露于日光或日光浴床很可能都是危险因素。
One of the established risk factors for melanoma is UV light, so both exposure to sun and exposure to tanning beds are probably risk factors.
目的探讨胰腺癌细胞(PC-3)胰岛素样生长因子-1受体(IGF- 1R)基因的定量表达,及其与细胞凋亡、成瘤性的关系。
Objective To explore Insulin like growth factor 1 receptor(IGF 1R)gene quantitative expression in human pancreatic cancer cells(PC 3) and the relationship of IGF 1R with apoptosis?tumorigenicity.
目的研究抑制素、表皮生长因子受体在人卵巢颗粒细胞瘤中的表达及临床意义。
Objective To investigate the expression of inhibin, epidermal growth factor receptor in human ovarian granulosa cell tumor and their clinical significance.
目的探讨血管内皮生长因子(VEGF)在脑星形细胞瘤中的表达及其与肿瘤生长、预后和血管生成的关系。
Objective to study the relationship between the expression of vascular endothelial growth factor (VEGF) and the angiogenesis, growth and prognosis in brain astrocytoma.
目的研究兔VX2肝移植瘤的微血管密度(MVD)和血管内皮生长因子(VEGF)与CT灌注成像各灌注参数的相关关系。
Objective to study the relationship of ct perfusion parameters with microvessel density (MVD) and vascular endothelial growth factor (VEGF) in rabbit VX2 liver tumor.
目的探讨人脑膜瘤血管内皮细胞生长因子(VEGF)的表达和微血管数量(MVQ)与肿瘤良恶性程度的关系。
Objective to investigate the relationship between the expression of vascular endothelial growth factor (VEGF), the microvessel quantity (MVQ) and the grade of human meningiomas.
结论:当其他的鉴别风险因子算术的控制后,转移瘤切除术对有肺转移性黑色素瘤患者仍有显著的生存优势。
CONCLUSIONS: When all other identified risk factors were controlled for mathematically, metastasectomy maintained a significant survival advantage for patients with pulmonary metastatic melanoma.
目的研究血管内皮生长因子(VEGF)表达与人脑转移瘤瘤周脑水肿(PTBE)的关系。
Objective to investigate the expression of vascular endothelial growth factor (VEGF) and its relationship with peritumoral brain edema (PTBE) in brain metastases.
背景:边缘区淋巴瘤是比较少见的B细胞淋巴瘤。边缘区淋巴瘤的转归和预后因子尚不明确。
Background: MZL are uncommon B-cell lymphomas. The outcomes and prognostic factors of MZL remain poorly defined.
雌激素是生理性促泌乳因子之一,已逐渐注意到其在泌乳素瘤形成中的作用。
Estrogen is one of the physiological lactation-promoting factors, and its effects in prolactinoma formation have been gradually noticed.
目的探讨胶质瘤细胞血小板源生长因子B链的纯合二聚体(PDGFBB)自分泌环活性与其细胞增殖和凋亡的关系。
Objective to investigate the relationship between activity of autocrine loop of platelet derived growth factor BB (PDGFBB), cell proliferation and apoptosis in gliomas.
目的研究多发性骨髓瘤(MM)细胞脑源性神经营养因子(BDNF)的表达水平及其与MM细胞诱导的血管新生的关系。
Objective To investigate the expression of brain-derived neurotrophic factor (BDNF) in multiple myeloma (MM) cells and the correlation between BDNF and MM angiogenesis.
目的探讨门静脉阻断对兔肝VX2移植瘤血管内皮生长因子(VEGF)表达的影响。
Objective To discuss the expression of vascular endothelial growth factor(VEGF)of hepatic VX2 tumor after portal vein occlusion in rabbits.
探讨晚期神经母细胞瘤(NB)患者血清血管内皮生长因子(VEGF)水平的意义。
To investigate the clinical significance of serum vascular endothelial growth factor (VEGF) level in patients with advanced neuroblastoma (NB).
目的探讨人脑胶质瘤中血管内皮细胞生长因子(VEGF)的表达与微血管数量(MVQ)和肿瘤良恶性程度的关系。
Objective to investigate the relationship between the expression of vascular endothelial growth factor (VEGF), the microvessel quantity (MVQ) and the grade in human brain gliomas.
目的观察血管内皮生长因子(VEGF)抗体对大鼠c6胶质瘤细胞凋亡的影响及对肿瘤生长的抑制作用。
Objective to observe the affect of vascular endothelial growth factor (VEGF) antibody on the cell apoptosis and growth of rat C6 glioma.
目的探讨应用动态增强磁共振成像(DCE MRI)评价的孤立性脑转移瘤血管通透性与血管内皮生长因子(VEGF)表达的空间分布相关性。
Objective to evaluate the correlation between vascular permeability by dynamic-contrast enhanced MRI (DCE-MRI) and vascular endothelial growth factor (VEGF) expression in solitary brain metastasis.
目的探讨甲状腺转录因子1 (TTF 1)和表面活性蛋白a、B (SP A,SP B)在肺硬化性血管瘤(PSH)中表达的生物学意义。
Objective to investigate the biologic significance of thyroid transcription factor-1 (TTF-1) and surfactant protein a (SP-A) and SP-B expression in pulmonary sclerosing hemangioma (PSH).
目的探讨小儿皮肤血管瘤各阶段肿瘤坏死因子相关凋亡诱导配体(TRAIL)的表达与细胞增殖和凋亡的关系。
Aim: to investigate the relationship between the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), cell proliferation and apoptosis in children's skin hemangioma.
目的:研究血管内皮生长因子(VEGF)反义rna对体外培养人脑垂体瘤细胞增殖和凋亡的影响。
Objective: to study the effect of VEGF antisense RNA on the proliferation activity and apoptosis of human pituitary adenoma cells in vitro.
目的:检测血管内皮生长因子(VEGF)和增殖细胞核抗原(pcna)在胶质瘤中表达,并探讨其与肿瘤恶性程度的关系。
Objective: To examine the expressions of VEGF and PCNA in gliomas, and investigate the possible relationship between their expressions and the degree of tumor malignancy.
新生血管大量形成在实体瘤的生长和转移中起着关键的作用。血管内皮生长因子(VEGF)是介导肿瘤血管生成的最主要因素。
New vessel formation plays a key role in tumor growth and transforming, and the Vascular endothelial growth factor (VEGF) is the most important factor inducing tumor vessel formation.
目的:探讨核糖核酸酶抑制因子对脑胶质瘤生长的抑制作用及可能机理。
Objective: to explore the role and mechanism of suppression of ribonuclease RNase inhibitor in the growth of glioma cells.
目的:探讨肿瘤坏死因子相关凋亡诱导配体(TRAIL)联合化疗药物治疗神经母细胞瘤(NB)的作用及其可能机制。
Objective: To explore the role of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL) combined with chemotherapeutic agents in treating neuroblastoma(NB) and the possible mechanism.
目的探讨用转粒细胞巨噬细胞集落刺激因子(GM CSF)基因瘤苗,联合白介素12 (IL 12)治疗小鼠t细胞淋巴瘤的方法。
Objective To study the method of immunotherapy against t cell lymphoma by tumor cells transfected by GM-CSF gene combined with interleukin 12 (IL-12).
目的:研究T细胞在巨噬细胞游走抑制因子(MIF)基因修饰的瘤苗诱导抗肿瘤免疫反应中的作用。
Objective: To investigate the role of t cell in the antitumor immune responses induced by MIF gene modified tumor vaccine.
目的:研究T细胞在巨噬细胞游走抑制因子(MIF)基因修饰的瘤苗诱导抗肿瘤免疫反应中的作用。
Objective: To investigate the role of t cell in the antitumor immune responses induced by MIF gene modified tumor vaccine.
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