其与甲状腺的发育有关,并且调控甲状腺球蛋白、甲状腺过氧化物酶和促甲状腺激素受体基因的转录。
TTF-1 is related to development of the thyroid gland and regulates and controls transcriptions of thyroglobulin(TG), thyroperoxidase(TPO), and thyrotropin(TSH) receptor genes.
目的克隆人促甲状腺激素受体胞外段基因,构建重组真核表达质粒,获得具有免疫学活性的纯化重组蛋白。
Objective to clone and construct the plasmid containing human thyroid stimulating hormone receptor (TSHR) gene ectodomain, and then identify the immunoreactivity of the purified recombinant protein.
在心肌细胞中,T3结合到细胞核中的甲状腺激素受体,其依次结合靶基因调节区中的甲状腺激素反应元件以调节转录。
In the cardiomyocyte, T3 binds to thyroid hormone receptors in the nucleus, which in turn bind to thyroid hormone response elements in the regulatory regions of target genes to regulate transcription.
在心肌细胞中,T3结合到细胞核中的甲状腺激素受体,其依次结合靶基因调节区中的甲状腺激素反应元件以调节转录。
In the cardiomyocyte, T3 binds to thyroid hormone receptors in the nucleus, which in turn bind to thyroid hormone response elements in the regulatory regions of target genes to regulate transcription.
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