例如,艾比特思和名为表皮生长因子受体(EGFR)的细胞表面蛋白的结合。
Erbitux, for example, binds to a cell-surface protein called epidermal growth-factor receptor (EGFR).
应用受体的放射配基结合分析法测定出甜菜碱对大鼠肝细胞膜表皮生长因子受体(EGF)及其酪氨酸蛋白激酶(TPK)有显著的结合抑制作用。
Using radioligand of binding assay of receptors determinates that betaine can inhibit the binding of EGF receptor with EGF and affect the TPK activity conspicuously.
表皮生长因子受体的三维结构通过同源蛋白模建的方法得到,而抑制剂和靶酶结合复合物结构则通过分子力学和分子动力学结合的方法计算得到。
The 3d structure of EGFR was constructed using homology modeling, and the complex structures between receptor and ligands were predicted by using molecular mechanics and molecular dynamics.
表皮生长因子受体的三维结构通过同源蛋白模建的方法得到,而抑制剂和靶酶结合复合物结构则通过分子力学和分子动力学结合的方法计算得到。
The 3d structure of EGFR was constructed using homology modeling, and the complex structures between receptor and ligands were predicted by using molecular mechanics and molecular dynamics.
应用推荐