例如,美国癌症协会发现,乳腺癌患者的生存率如此制高的一个原因就是有很好的检查手段能在疾病的早期发现这一肿瘤。
For example, the American Cancer Society finds that a reason breast cancer survival rates are so high is that there are good methods for early detection of tumors.
显然,最重要的终点是总体生存率。
过去的数十年里,肿瘤生存率有着显著的提升。
Over the past few decades, cancer survival rates have significantly increased.
研究人员称:“老鼠接受不同剂量的提取物后,HE 肿瘤大小在记录中呈剂量依赖性下降,此外,还能显著提高生存率。”
Mice received different doses of the extract, with a dose-dependent decrease in HE tumour size recorded, in addition to “significantly enhanced survival”, said the researchers.
另外,生存率很大程度上受复发的治疗选择影响。
In addition, survival is heavily influenced by the choice of treatment for recurrences.
相对无效的药物需要有效的抢救药物,而这可能掩盖了药物对于生存率的真正作用。
Relatively ineffective drugs will require effective salvage drugs, and this may obscure the true effects of a drug with regard to survival.
在进行死因分析时,接受伊马替尼治疗的患者的总体生存率为88%。
The estimated overall survival rate for patients receiving Gleevec was 88% when considering deaths from all causes.
虽然治疗方式从药物到心脏移植有很多,但高达40%的患者在确诊一年内去世,心力衰竭的生存率比许多癌症都低。
Treatments range from drugs to transplants but with up to 40 per cent of those affected dying within a year of diagnosis, heart failure has worse survival rate than many cancers.
因此,替代终点如反应率和无进展生存率被普遍接受,尽管各方意识到风险所在。
Thus, surrogate endpoints like response rate and progression-free survival are commonly accepted, although all parties involved realize the risk involved.
反应率通常仅限于在二期试验中,因为它已经说明与整体生存率的关系并非始终存在。
The use of response rates is usually confined to Phase II, as it has been shown that the relation to overall survival is not always present.
通过降低人体温度来提高病患生存率的想法其实是老调重弹了。
The idea of chilling people to promote survival is far from new.
本次研究表明该疗法可能会减少肿瘤治疗过程中的压力,但却不太可能会提高女性的生存率。
The study is rare because while it makes sense that therapy might ease some of the stress of cancer treatment, few studies have shown it can boost a woman's survival.
华盛顿--周日医生说,一项新的关于对人类免疫缺陷病毒最佳治疗时间的分析发现:早期迅速的治疗可以提高患者的生存率。
WASHINGTON —A new analysis of the best time to begin HIV treatment found that starting early sharply improves survival, doctors said Sunday.
华盛顿——周日医生说,一项新的关于对人类免疫缺陷病毒最佳治疗时间的分析发现:早期迅速的治疗可以提高患者的生存率。
WASHINGTON - a new analysis of the best time to begin HIV treatment found that starting early sharply improves survival, doctors said Sunday.
在年龄相关组中生存率曲线呈现了斜坡式的变化,显示更年轻的妇女有更好的预后(表3.2)。
There is a steep gradient in survival by age, with younger women having a better prognosis (Figure 3.2).
例如,与人合住的人的生存率只比独居的人高19%。
For instance, people who lived withothers had just a 19 percent survival benefit compared with those who livedalone.
卵巢癌生存率在最近的35年中有所提高,但长期生存率依然较低(图3.1)。
Survival for ovarian cancer has improved over the last 35 years, but long-term rates are still low (Figure 3.1).
“事实上,一天内积极的情绪对生存率的预测令人惊异,”加利福尼亚大学心理学教授Sonja Lyubomirsky说。
"The fact that positive emotions in one day predicted survival is pretty amazing," says Sonja Lyubomirsky, a psychology professor at the University of California, Riverside.
Joy Lawn说,提高新生儿生存率不仅需要钱。
Improving newborn survival rates takes more than money, says Joy Lawn.
第二项研究显示Ipilimumab(商品名为Yervoy)也能延长有合并症的黑色素瘤患者生存率。
A second study showed that the recently approved drug Ipilimumab, sold under the name Yervoy, also extends survival for melanoma patients with advanced disease.
Kitahata说有理由相信早期用药治疗可以获得更高的生存率。
"There's reason to believe you would have even better survival using drugs available now," she says.
生存率分析使用了Kaplan -Meier方法。
Kaplan-Meier methods were used to compute the survival analyses.
接收激进手术治疗的病人身体变型更大,也更容易受到附属疾病的困扰,但是慕克吉写道他们“在生存率、复发率或死亡率上却没有得到任何好处。”
The latter group paid heavily in disfigurement and ancillary ill health, but, Mukherjee writes, they “accrued no benefits in survival, recurrence, or mortality.”
每项研究统计了6年和21年间的步速测量和生存率。
Each study had collected walking speed measurements and survival rates dating back between six and 21 years.
无论如何,除了90年代初期十分高龄的患者总的生存率还是都有所提高。
However, survival has improved in all but the very oldest ages since the early 1990s.
老鼠被移植癌细胞后,食用苹果多酚水溶液,在生存率、生活质量方面,都有比较好的抗癌功效。
After consuming liquid soluble apple polyphenol mice that have been transplanted with cancer cells have greater effect against cancer whether in terms of survivability and standard of living.
肺癌患者的生存率容易被过去的统计数据所误导,因为美国癌症协会最新的数据仍是基于在1998年至2000年间所获取的数据。
Survival rates for lung cancer can be misleading. The American Cancer Society's latest data is based on people who were diagnosed between 1998 and 2000.
但大多数肿瘤的发病、生存率和治疗模式都已发生了变化。
However, incidence, survival, and practice patterns have been changing for the majority of cancers.
我们知道HCV患者疾病复发常常是导致其生存率很低的原因:他们常常会因为肝硬化复发而死亡。
We know the worst survival in HCV is because they get recurrent disease: they get recurred cirrhosis and they die of recurrent cirrhosis.
我们知道HCV患者疾病复发常常是导致其生存率很低的原因:他们常常会因为肝硬化复发而死亡。
We know the worst survival in HCV is because they get recurrent disease: they get recurred cirrhosis and they die of recurrent cirrhosis.
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